Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIF11 | P52732 | 1/20 | 0.32 |
| ▸ | HTR6 | P50406 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13060991 | 0.81 | HPGD (0.37) | NPC1MAPTRAB9A | |
| SCHEMBL25957468 | 0.79 | SIGMAR1 (0.37) | POLBMAPTRAB9A | |
| SCHEMBL18698222 | 0.79 | SIGMAR1 (0.37) | HTR6MAPT | |
| SCHEMBL19292565 | 0.79 | BRD4 (0.45) | NPC1MAPTRAB9A | |
| SCHEMBL25867807 | 0.78 | KMO (0.33) | — | |
| SCHEMBL5475416 | 0.75 | NPC1 (0.36) | KIF11HTR6NPC1POLBMAPT | |
| SCHEMBL12953238 | 0.75 | PNMT (0.33) | — | |
| SCHEMBL8521796 | 0.73 | POLB (0.43) | HTR6POLBMAPTRAB9A | |
| SCHEMBL18684822 | 0.71 | GPR3 (0.38) | KIF11NPC1POLBMAPTRAB9A | |
| SCHEMBL5476090 | 0.71 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1681284-A1 | AROMATIC POLYAMINE DERIVATIVE | Daicel Chemical Industries, Ltd. (JP) | 2006-07-19 | — | — | EP | disclosed |