Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.37 |
| ▸ | PRKCI | P41743 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 3/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | HTR6 | P50406 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.32 |
| ▸ | GAA | P10253 | 3/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 2/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | CASP1 | P29466 | 1/20 | 0.31 |
| ▸ | GRIN2D | O15399 | 2/20 | 0.31 |
| ▸ | GRIN3B | O60391 | 2/20 | 0.31 |
| ▸ | GRIN1 | Q05586 | 2/20 | 0.31 |
| ▸ | GRIN2A | Q12879 | 2/20 | 0.31 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.31 |
| ▸ | GRIN2C | Q14957 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20860303 | 0.84 | SIGMAR1 (0.37) | SIGMAR1PRKCIMAPTCYP1A2CYP2C9 | |
| SCHEMBL18474287 | 0.80 | PRKCI (0.38) | SIGMAR1PRKCIMAPTCYP1A2CYP2C9 | |
| SCHEMBL5703629 | 0.79 | KIF11 (0.32) | MAPTHTR6 | |
| SCHEMBL13060991 | 0.78 | HPGD (0.37) | MAPTCYP1A2CYP2C9CYP2C19ALDH1A1 | |
| SCHEMBL25957468 | 0.76 | SIGMAR1 (0.37) | SIGMAR1MAPTALDH1A1GAAHTT | |
| SCHEMBL12953238 | 0.76 | PNMT (0.33) | ALDH1A1HRH3SMN1; SMN2 | |
| SCHEMBL8033091 | 0.73 | PRKCI (0.41) | SIGMAR1PRKCIMAPTCYP1A2CYP2C9 | |
| SCHEMBL26405492 | 0.72 | ALDH1A1 (0.52) | SIGMAR1MAPTCYP1A2ALDH1A1GAA | |
| SCHEMBL784058 | 0.72 | PRKCI (0.53) | SIGMAR1PRKCIMAPTCYP1A2CYP2C9 | |
| SCHEMBL3110533 | 0.70 | ALDH1A1 (0.54) | SIGMAR1PRKCIMAPTCYP1A2CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9610368-B2 | Radiolabelled glutaminyl cyclase (QC) inhibitors and uses of same | PROBIODRUG AG (DE) | 2017-04-04 | — | — | US | disclosed |