Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.51 |
| ▸ | PPARA | Q07869 | 2/20 | 0.49 |
| ▸ | CTRB1 | P17538 | 2/20 | 0.49 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | CTSB | P07858 | 2/20 | 0.48 |
| ▸ | CTSK | P43235 | 2/20 | 0.46 |
| ▸ | SPPL2A | Q8TCT8 | 1/20 | 0.45 |
| ▸ | TACR1 | P25103 | 2/20 | 0.45 |
| ▸ | CCR1 | P32246 | 2/20 | 0.45 |
| ▸ | CTSL | P07711 | 2/20 | 0.44 |
| ▸ | CTSS | P25774 | 2/20 | 0.44 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5704587 | 0.93 | TRPM8 (0.57) | TRPM8CTRB1CTSBCTSKTACR1 | |
| SCHEMBL5704586 | 0.87 | LTA4H (0.53) | TRPM8PPARACTRB1 | |
| SCHEMBL11422143 | 0.85 | PPARA (0.56) | TRPM8PPARACTRB1TP53CTSB | |
| SCHEMBL6282998 | 0.84 | CTSB (0.56) | TRPM8CTRB1CTSBCTSKTACR1 | |
| SCHEMBL7428630 | 0.83 | TRPM8 (0.55) | TRPM8CTRB1CTSBCTSKTACR1 | |
| SCHEMBL7321385 | 0.83 | TRPM8 (0.55) | TRPM8CTRB1CTSBCTSKTACR1 | |
| SCHEMBL7268961 | 0.82 | TRPM8 (0.54) | TRPM8CTRB1CTSBCTSKTACR1 | |
| SCHEMBL9724730 | 0.81 | TRPM8 (0.53) | TRPM8CTRB1CTSBCTSKTACR1 | |
| SCHEMBL7335755 | 0.81 | TRPM8 (0.53) | TRPM8CTRB1CTSBCTSKTACR1 | |
| SCHEMBL7807953 | 0.81 | CTSD (0.63) | TRPM8CTSBCTSKCTSLCTSS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1243576-B1 | PROCESSES FOR PRODUCING (AMINOMETHYL)TRIFLUOROMETHYLCARBINOL DERIVATIVES | DAINIPPON SUMITOMO PHARMA CO (JP) | 2006-10-11 | — | — | EP | disclosed |
| US-6646150-B1 | Reacting 1,3-oxazolidin-5-one derivative with trialkyl-(trifluoromethyl)silane; removing trialkylsilyl group; reductive decyclization | DAINIPPON PHARMACEUTICAL CO., LTD. (JP) | 2003-11-11 | — | — | US | disclosed |
| EP-1243576-A1 | PROCESSES FOR PRODUCING (AMINOMETHYL)TRIFLUOROCARBINOL DERIVATIVES | Dainippon Pharmaceutical Co., Ltd. (JP) | 2002-09-25 | — | — | EP | disclosed |