Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIF11 | P52732 | 1/20 | 0.55 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.53 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.53 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.53 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.53 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.53 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.53 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.53 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.52 |
| ▸ | DDAH1 | O94760 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | NPC1 | O15118 | 2/20 | 0.48 |
| ▸ | RAB9A | P51151 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5705176 | 0.87 | TDP1 (0.45) | KIF11GRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL5705035 | 0.80 | TDP1 (0.56) | KIF11GRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL81433 | 0.76 | KIF11 (0.88) | KIF11TDP1DDAH1POLBKDM4E | |
| SCHEMBL1278440 | 0.76 | ALDH1A1 (0.61) | KIF11GRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL166139 | 0.76 | KIF11 (0.55) | KIF11GRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL12824893 | 0.76 | KIF11 (0.55) | KIF11GRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL10793021 | 0.75 | ALDH1A1 (0.58) | GRIN2DGRIN3BGRIN1GRIN2AGRIN2B | |
| Hydrochloric Acid SCHEMBL5478555 | 0.74 | KIF11 (0.53) | KIF11GRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL10882395 | 0.74 | ALDH1A1 (0.59) | KIF11GRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL9725052 | 0.74 | KMT2A (0.53) | KIF11GRIN2DGRIN3BGRIN1GRIN2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7176164-B2 | 1,3-selenazolin derivatives and process for preparing the same | GIFU UNIVERSITY (JP) | 2007-02-13 | — | — | US | disclosed |
| US-20030158239-A1 | Novel 1,3-selenazolin derivatives and process for preparing the same | GIFU UNIVERSITY (JP) | 2003-08-21 | — | — | US | disclosed |
| EP-1323714-A1 | 1,3-selenazole derivatives and their use as anticancer drugs or as agrochemicals | President of Gifu University (JP) | 2003-07-02 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030158239-A1 | Novel 1,3-selenazolin derivatives and process for preparing the same | SELENOI, SCLY, SULT1A1 | KIF11 3433/4885GRIN2D 3867/4885GRIN3B 3935/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.