⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4088275 | 0.76 | — | — | |
| SCHEMBL21611735 | 0.75 | — | — | |
| SCHEMBL3475452 | 0.75 | — | — | |
| SCHEMBL9654791 | 0.74 | — | — | |
| SCHEMBL4258104 | 0.72 | NPC1 (0.37) | — | |
| SCHEMBL1697828 | 0.69 | TRPA1 (0.35) | — | |
| SCHEMBL28178876 | 0.68 | — | — | |
| SCHEMBL2121390 | 0.67 | NOS3 (0.35) | — | |
| SCHEMBL581261 | 0.67 | NPC1 (0.41) | — | |
| SCHEMBL8444804 | 0.65 | NPC1 (0.34) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6589507-B1 | Foaming antacid suspension tablets | DR. REGENOLD GMBH (DE) | 2003-07-08 | — | — | US | claimed |
| US-9757415-B2 | Composition comprising solanum glaucophyllum for preventing and/or treating hypocalcaemia and for stabilizing blood calcium levels | HERBONIS AG (CH) | 2017-09-12 | — | — | US | disclosed |
| US-20170156837-A1 | DISPENSER AND METHOD FOR APPLYING A TOOTH WHITENING COMPOSITION | COLGATE PALMOLIVE CO (US) | 2017-06-08 | — | — | US | disclosed |
| US-9610148-B2 | Applicator and method for applying a tooth whitening composition | COLGATE-PALMOLIVE COMPANY (US) | 2017-04-04 | — | — | US | disclosed |
| US-20140356807-A1 | APPLICATOR AND METHOD FOR APPLYING A TOOTH WHITENING COMPOSITION | COLGATE PALMOLIVE CO (US) | 2014-12-04 | — | — | US | disclosed |
| US-20140322322-A1 | COMPOSITION COMPRISING SOLANUM GLAUCOPHYLLUM FOR PREVENTING AND/OR TREATING HYPOCALCAEMIA AND FOR STABILIZING BLOOD CALCIUM LEVELS | HERBONIS AG (CH) | 2014-10-30 | — | — | US | disclosed |
| US-8815216-B2 | Applicator and method for applying a tooth whitening composition | COLGATE-PALMOLIVE COMPANY (US) | 2014-08-26 | — | — | US | disclosed |
| CN-101161244-A | Nimodipine tablet and its preparing method | SHANGHAI SHIKANGTE PHARMACEUTI (CN) | 2008-04-16 | — | — | CN | disclosed |
| US-20060275225-A1 | Applicator and method for applying a tooth whitening composition | PRENCIPE MICHAEL | 2006-12-07 | — | — | US | disclosed |
| EP-1686919-A1 | AN APPLICATOR AND METHOD FOR APPLYING A TOOTH WHITENING COMPOSITION | Colgate-Palmolive Company (US) | 2006-08-09 | — | — | EP | disclosed |
| CN-1245976-C | Pharmaceutical formulations in hydroxypropylmenthyl cellulose capsules | PHARMACIA & UPJOHN SPA (IT) | 2006-03-22 | — | — | CN | disclosed |
| WO-2005037127-A1 | AN APPLICATOR AND METHOD FOR APPLYING A TOOTH WHITENING COMPOSITION | COLGATE-PALMOLIVE COMPANY (US) | 2005-04-28 | — | — | WO | disclosed |
| WO-2005019176-A1 | SUBSTITUTED AMINO-AZA-CYCLOHEXANES | ACTELION PHARMACEUTICALS LTD (CH) | 2005-03-03 | — | — | WO | disclosed |
| CN-1327387-A | Pharmaceutical formulations in the form of hydroxypropylmethylcellulose capsules | PHARMACIA & UPJOHN SPA (IT) | 2001-12-19 | — | — | CN | disclosed |
| CN-2323782-Y | Constant release paster for metoprolol | WANG LIXIA (CN) | 1999-06-16 | — | — | CN | disclosed |
| WO-1990002133-A1 | METHOD FOR PREPARING SUCRALFATE AND AAI-10001 | FORMULATIONS DEVELOPMENT LABORATORIES, INC. (US) | 1990-03-08 | — | — | WO | disclosed |