Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | ACHE | P22303 | 2/20 | 0.40 |
| ▸ | SLC18A2 | Q05940 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | GLA | P06280 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6686461 | 0.75 | TAAR1 (0.47) | ALDH1A1 | |
| SCHEMBL4258104 | 0.73 | NPC1 (0.37) | NPC1L3MBTL1ALDH1A1 | |
| SCHEMBL4088275 | 0.73 | — | — | |
| SCHEMBL9654791 | 0.72 | — | — | |
| SCHEMBL3639817 | 0.71 | KDM4E (0.42) | NPC1L3MBTL1ACHEALDH1A1 | |
| SCHEMBL28298668 | 0.70 | CALM1 (0.50) | ACHESLC18A2HPGDALDH1A1GLA | |
| SCHEMBL3475452 | 0.69 | — | — | |
| SCHEMBL22125307 | 0.69 | ACHE (0.38) | NPC1L3MBTL1ACHEHPGDALDH1A1 | |
| SCHEMBL22125305 | 0.69 | ACHE (0.38) | NPC1L3MBTL1ACHEHPGDALDH1A1 | |
| SCHEMBL31427474 | 0.69 | ACHE (0.38) | NPC1L3MBTL1ACHEHPGDALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 37 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2709977-B1 | USE OF BENZOTROPOLONE DERIVATIVES AS PHOTOSTABILIZER AND ANTIOXIDANT FOR STABILIZATION OF BODY-CARE AND HOUSEHOLD PRODUCTS. | BASF SE (DE) | 2018-09-05 | — | — | EP | disclosed |
| US-9707417-B2 | Use of benzotropolone derivatives as UV absorbers and antioxidants and their use in sunscreens and/or cosmetic compositions | BASF SE (DE) | 2017-07-18 | — | — | US | disclosed |
| US-9663442-B2 | Stabilization of household, body-care and food products by using benzotropolone containing plant extracts and/or related benzotropolone derivatives | BASF SE (DE) | 2017-05-30 | — | — | US | disclosed |
| CN-102238983-B | Benzotropolone derivatives is as UV absorbent and the purposes of antioxidant and the purposes in sun-screening agent and/or cosmetic composition thereof | 巴斯夫欧洲公司 | 2016-08-24 | — | — | CN | disclosed |
| EP-2296760-B1 | USE OF BENZOTROPOLONE DERIVATIVES AS UV ABSORBERS AND ANTIOXIDANTS AND THEIR USE IN SUNSCREENS AND/OR COSMETIC COMPOSITIONS | BASF SE (DE) | 2016-03-16 | — | — | EP | disclosed |
| US-20150353470-A1 | STABILIZATION OF HOUSEHOLD, BODY-CARE AND FOOD PRODUCTS BY USING BENZOTROPOLONE CONTAINING PLANT EXTRACTS AND/OR RELATED BENZOTROPOLONE DERIVATIVES | BASF SE (DE) | 2015-12-10 | — | — | US | disclosed |
| US-8894993-B2 | Mitochondria-targeted antioxidants | NATREON INC. (US) | 2014-11-25 | — | — | US | disclosed |
| US-8784853-B2 | Stabilization of household, body-care and food products by using benzotropolone containing plant extracts and/or related benzotropolone derivatives | BASF SE (DE) | 2014-07-22 | — | — | US | disclosed |
| EP-2709977-A2 | USE OF BENZOTROPOLONE DERIVATIVES AS PHOTOSTABILIZER AND ANTIOXIDANT FOR STABILIZATION OF BODY-CARE AND HOUSEHOLD PRODUCTS. | BASF SE (DE) | 2014-03-26 | — | — | EP | disclosed |
| US-8383088-B2 | Coumestan-like antioxidants and UV absorbants | BASF SE (DE) | 2013-02-26 | — | — | US | disclosed |
| US-7150876-B2 | Methods for stabilizing ingredients within cosmetics, personal care and household products | MERCK PATENT GMBH (DE) | 2006-12-19 | — | — | US | disclosed |
| EP-1635777-A1 | PHOTOSTABLE ORGANIC SUNSCREEN COMPOSITION | MERCK PATENT GmbH (DE) | 2006-03-22 | — | — | EP | disclosed |
| US-20050244349-A1 | Methods for stabilizing ingredients within cosmetics, personal care and household products | SUSONITY Commercial GmbH (DE) | 2005-11-03 | — | — | US | disclosed |
| EP-1591099-A2 | Methods for stabilizing ingredients within cosmetics, personal care and household products | MERCK PATENT GmbH (DE) | 2005-11-02 | — | — | EP | disclosed |
| US-6831191-B2 | Blocking ultraviolet radiation on skin | EM INDUSTRIES | 2004-12-14 | — | — | US | disclosed |
| WO-2004105712-A1 | PHOTOSTABLE ORGANIC SUNSCREEN COMPOSITION | MERCK PATENT GMBH (DE) | 2004-12-09 | — | — | WO | disclosed |
| US-20040247536-A1 | Photo stable organic sunscreen compositions | EMD CHEMICALS, INC. | 2004-12-09 | — | — | US | disclosed |
| US-20030157035-A1 | PHOTO STABLE ORGANIC SUNSCREEN COMPOUNDS WITH ANTIOXIDANT PROPERTIES AND COMPOSITIONS OBTAINED THEREFROM | EM INDUSTRIES | 2003-08-21 | — | — | US | disclosed |
| US-6602515-B2 | Alpha-acetyl-3,5-dimethoxy-4-hydroxy cinnamate ester; dipalmitoyl-3,5- dimethoxy-4-hydroxy benzylidene malonate or amide derivatives | EM INDUSTRIES | 2003-08-05 | — | — | US | disclosed |
| US-20030108492-A1 | PHOTO STABLE ORGANIC SUNSCREEN COMPOUNDS WITH ANTIOXIDANT PROPERTIES AND COMPOSITIONS OBTAINED THEREFROM | EM INDUSTRIES | 2003-06-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050244349-A1 | Methods for stabilizing ingredients within cosmetics, personal care and household products | CUTA, TYR, LAGE3 | NPC1 4261/4885L3MBTL1 2759/4885ACHE 1309/4885 |
| US-20030157035-A1 | PHOTO STABLE ORGANIC SUNSCREEN COMPOUNDS WITH ANTIOXIDANT PROPERTIES AND COMPOSITIONS OBTAINED THEREFROM | ERCC1, ERCC4, OGG1 | NPC1 1850/4885L3MBTL1 2383/4885ACHE 2354/4885 |
| US-20030108492-A1 | PHOTO STABLE ORGANIC SUNSCREEN COMPOUNDS WITH ANTIOXIDANT PROPERTIES AND COMPOSITIONS OBTAINED THEREFROM | ERCC1, ERCC4, OGG1 | NPC1 1478/4885L3MBTL1 2890/4885ACHE 2154/4885 |
| US-20150353470-A1 | STABILIZATION OF HOUSEHOLD, BODY-CARE AND FOOD PRODUCTS BY USING BENZOTROPOLONE CONTAINING PLANT EXTRACTS AND/OR RELATED BENZOTROPOLONE DERIVATIVES | CBR3, CBR1, CYP8B1 | NPC1 3943/4885L3MBTL1 1318/4885ACHE 2194/4885 |
| US-20040247536-A1 | Photo stable organic sunscreen compositions | SUN2, CCNB1, TYR | NPC1 2349/4885L3MBTL1 3958/4885ACHE 2552/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.