Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 2/20 | 0.41 |
| ▸ | CA9 | Q16790 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | HBB | P68871 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | CASP3 | P42574 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | SCN2A | Q99250 | 2/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | CES1 | P23141 | 1/20 | 0.38 |
| ▸ | ELANE | P08246 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5706500 | 0.82 | CA12 (0.47) | CA12CA9ALDH1A1HBBHSD17B10 | |
| SCHEMBL11611823 | 0.80 | ELANE (0.42) | CA12CA9ALDH1A1HSD17B10LMNA | |
| SCHEMBL14477084 | 0.80 | CA12 (0.40) | CA12CA9ALDH1A1HBBHSD17B10 | |
| SCHEMBL5706512 | 0.80 | KMT2A (0.44) | CA12CA9ALDH1A1HBBHSD17B10 | |
| SCHEMBL22926344 | 0.79 | POLB (0.37) | CA12CA9ALDH1A1HBBHSD17B10 | |
| SCHEMBL9944717 | 0.77 | CASP3 (0.43) | CA12CA9ALDH1A1HBBHSD17B10 | |
| SCHEMBL2156119 | 0.76 | CASP3 (0.46) | ALDH1A1CASP3MEN1KMT2ANPC1 | |
| SCHEMBL30472938 | 0.76 | CASP3 (0.46) | ALDH1A1CASP3MEN1KMT2ANPC1 | |
| SCHEMBL15033556 | 0.76 | LMNA (0.40) | CA12CA9ALDH1A1HBBHSD17B10 | |
| SCHEMBL10335755 | 0.76 | ALDH1A1 (0.43) | CA12CA9ALDH1A1HBBHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1311493-B1 | SYNTHESIS OF MACROCYCLIC TETRAAMIDO LIGANDS USEFUL AS BLEACHING CATALYSTS | UNIV CARNEGIE MELLON (US) | 2006-11-02 | — | — | EP | disclosed |
| US-6992184-B2 | Macrocyclic tetraamido ligands as bleaching catalysts and synthesis thereof | CARNEGIE MELLON UNIVERSITY (US) | 2006-01-31 | — | — | US | disclosed |
| US-20030168630-A1 | Macrocyclic tetraamido ligands as bleaching catalysts and synthesis thereof | CARNEGIE MELLON UNIVERSITY | 2003-09-11 | — | — | US | disclosed |
| EP-1311493-A1 | MACROCYCLIC TETRAAMIDO LIGANDS AS BLEACHING CATALYSTS AND SYNTHESIS THEREOF | UNILEVER PLC (GB) | 2003-05-21 | — | — | EP | disclosed |
| WO-2002016330-A1 | MACROCYCLIC TETRAAMIDO LIGANDS AS BLEACHING CATALYSTS AND SYNTHESIS THEREOF | UNILEVER PLC (GB) | 2002-02-28 | — | — | WO | disclosed |
| EP-0333938-B1 | 2-HYDROXY-3-ARYLOXY-PROPYLAMINE DERIVATIVES HAVING CARDIOVASCULAR ACTIVITY | ZAMBON GROUP S.p.A. (IT) | 1993-04-14 | — | — | EP | disclosed |
| EP-0333938-A1 | 2-Hydroxy-3-aryloxy-propylamine derivatives having cardiovascular activity | ZAMBON GROUP S.p.A. (IT) | 1989-09-27 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030168630-A1 | Macrocyclic tetraamido ligands as bleaching catalysts and synthesis thereof | TYR, TBCB, PPOX | CA12 3429/4885CA9 4224/4885ALDH1A1 2858/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.