Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX3 | P56373 | 1/20 | 0.31 |
| ▸ | P2RX2 | Q9UBL9 | 1/20 | 0.31 |
| ▸ | DHFR | P00374 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4648511 | 0.77 | PDXK (0.38) | P2RX3P2RX2DHFR | |
| SCHEMBL26632902 | 0.77 | — | — | |
| SCHEMBL18343010 | 0.76 | KAT2B (0.35) | — | |
| SCHEMBL5708643 | 0.75 | DHFR (0.33) | P2RX3P2RX2DHFR | |
| SCHEMBL23064182 | 0.74 | ALDH1A1 (0.32) | — | |
| SCHEMBL4648722 | 0.74 | TYR (0.33) | — | |
| SCHEMBL23970881 | 0.73 | GABRA1 (0.39) | P2RX3P2RX2 | |
| SCHEMBL21598749 | 0.73 | ALDH1A1 (0.41) | — | |
| SCHEMBL4649636 | 0.72 | PDCD1LG2 (0.35) | P2RX3P2RX2DHFR | |
| SCHEMBL2185134 | 0.70 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1718613-A1 | PYRIDINE DERIVATIVES AND THEIR USE AS CB2 RECEPTOR MODULATORS | GLAXO GROUP LIMITED (GB) | 2006-11-08 | — | — | EP | disclosed |
| WO-2005080342-A1 | PYRIDINE DERIVATIVES AND THEIR USE AS CB2 RECEPTOR MODULATORS | GLAXO GROUP LIMITED (GB) | 2005-09-01 | — | — | WO | disclosed |