Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.62 |
| ▸ | ALDH3A1 | P30838 | 1/20 | 0.62 |
| ▸ | ALDH1A3 | P47895 | 1/20 | 0.62 |
| ▸ | MAPT | P10636 | 7/20 | 0.50 |
| ▸ | MEN1 | O00255 | 6/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | BCHE | P06276 | 2/20 | 0.48 |
| ▸ | ACHE | P22303 | 2/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | CAPN1 | P07384 | 1/20 | 0.46 |
| ▸ | CTSL | P07711 | 1/20 | 0.46 |
| ▸ | CTSB | P07858 | 1/20 | 0.46 |
| ▸ | CTSS | P25774 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5709303 | 1.00 | ALDH1A1 (0.62) | ALDH1A1ALDH3A1ALDH1A3MAPTMEN1 | |
| SCHEMBL133495 | 0.92 | ALDH1A1 (0.57) | ALDH1A1ALDH3A1ALDH1A3MAPTMEN1 | |
| SCHEMBL133494 | 0.92 | ALDH1A1 (0.57) | ALDH1A1ALDH3A1ALDH1A3MAPTMEN1 | |
| SCHEMBL12144183 | 0.85 | NFE2L2 (0.53) | ALDH1A1ALDH3A1ALDH1A3MAPTMEN1 | |
| SCHEMBL21591022 | 0.84 | ALDH1A1 (0.88) | ALDH1A1ALDH3A1ALDH1A3MAPTMEN1 | |
| SCHEMBL8529392 | 0.83 | MAPT (0.53) | ALDH1A1ALDH3A1ALDH1A3MAPTMEN1 | |
| SCHEMBL11212282 | 0.83 | MAPT (0.53) | ALDH1A1ALDH3A1ALDH1A3MAPTMEN1 | |
| SCHEMBL5709308 | 0.83 | ALDH1A1 (0.52) | ALDH1A1ALDH3A1ALDH1A3MAPTMEN1 | |
| SCHEMBL7944752 | 0.81 | APP (0.65) | ALDH1A1MAPTMEN1KMT2ALMNA | |
| SCHEMBL7944755 | 0.81 | APP (0.65) | ALDH1A1MAPTMEN1KMT2ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1052291-B1 | Fluorescent stain containing pyrylium salt or its similar salt, detection method of nucleic acid by use of it | CANON KK (JP) | 2006-10-25 | — | — | EP | disclosed |
| EP-0684239-B1 | A method for detecting a target substance in a sample, utilizing pyrylium compound | CANON KK (JP) | 2003-12-10 | — | — | EP | disclosed |
| EP-0643140-B1 | Determination of nucleic acid by PCR, measurement of number of microbial cells, genes, or gene-copies by PCR, and measuring-kit employed for the same | CANON KK (JP) | 2001-10-31 | — | — | EP | disclosed |
| EP-0603783-B1 | Fluorescent stain containing pyrylium salt or its similar salt, detection method of nucleic acid by use of it | CANON KK (JP) | 2001-09-26 | — | — | EP | disclosed |
| US-6242477-B1 | RADIATING AND KILLING CANCER CELLS | CANON KABUSHIKI KAISHA (JP) | 2001-06-05 | — | — | US | disclosed |
| US-6156506-A | Method for detecting a target substance in a sample, utilizing pyrylium compound | CANON KABUSHIKI KAISHA (JP) | 2000-12-05 | — | — | US | disclosed |
| EP-1052291-A2 | Fluorescent stain containing pyrylium salt or its similar salt, detection method of nucleic acid by use of it | CANON KABUSHIKI KAISHA (JP) | 2000-11-15 | — | — | EP | disclosed |
| US-6124342-A | RADIATION THERAPY TO INDUCE DEATH OF THE CANCER CELLS | CANON KK (JP) | 2000-09-26 | — | — | US | disclosed |
| US-6022961-A | HYBRIDIZATION PROBE OF SINGLE-STRANDED NUCLEIC ACID HAVING NUCLEOTIDE SEQUENCE COMPLEMENTARY TO TARGET AND WITH COVALENTLY BOUND DYE | CANON KABUSHIKI KAISHA (JP) | 2000-02-08 | — | — | US | disclosed |
| US-5670315-A | AMPLIFICATION; QUANTITATIVE ANALYSIS | CANON KABUSHIKI KAISHA (JP) | 1997-09-23 | — | — | US | disclosed |
| US-5624798-A | Detection method of nucleic acid by use of fluorescent pyrylium stain in intercalation into nucleic acids | CANON KABUSHIKI KAISHA (JP) | 1997-04-29 | — | — | US | disclosed |
| EP-0684239-A1 | A method for detecting a target substance in a sample, utilizing pyrylium compound | CANON KABUSHIKI KAISHA (JP) | 1995-11-29 | — | — | EP | disclosed |
| EP-0659407-A1 | Pharmaceutical compositions containing pyrylium compounds, pyrylium salts and process for manufacturing a medicament containing the aforesaid compounds | CANON KABUSHIKI KAISHA (JP) | 1995-06-28 | — | — | EP | disclosed |
| EP-0643140-A1 | Determination of nucleic acid by PCR, measurement of number of microbial cells, genes, or gene-copies by PCR, and measuring-kit employed for the same | CANON KABUSHIKI KAISHA (JP) | 1995-03-15 | — | — | EP | disclosed |
| EP-0603783-A1 | Fluorescent stain containing pyrylium salt or its similar salt, detection method of nucleic acid by use of it, and fluorescent staining method of biological sample | CANON KABUSHIKI KAISHA (JP) | 1994-06-29 | — | — | EP | disclosed |