SCHEMBL5709308

SCHEMBL5709308

CCN(CC)c1ccc(C=O)c(C=Cc2ccccc2)c1

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 9/20 0.52
L3MBTL1 Q9Y468 2/20 0.52
ALDH3A1 P30838 1/20 0.49
ALDH1A3 P47895 1/20 0.49
MAPT P10636 10/20 0.47
KDM4E B2RXH2 4/20 0.47
MEN1 O00255 7/20 0.45
KMT2A Q03164 7/20 0.45
MAPK1 P28482 2/20 0.45
TDP1 Q9NUW8 2/20 0.45
USP2 O75604 1/20 0.45
CTNNB1 P35222 1/20 0.45
ATM Q13315 1/20 0.45
RXFP1 Q9HBX9 1/20 0.45
NPSR1 Q6W5P4 2/20 0.44
HPGD P15428 2/20 0.44
CNR2 P34972 1/20 0.43
GAA P10253 2/20 0.43
HTT P42858 1/20 0.43
BACE1 P56817 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5709304 0.83 ALDH1A1 (0.62) ALDH1A1L3MBTL1ALDH3A1ALDH1A3MAPT
SCHEMBL7944758 0.83 RELA (0.58) L3MBTL1MAPTKDM4EMEN1KMT2A
SCHEMBL5709303 0.83 ALDH1A1 (0.62) ALDH1A1L3MBTL1ALDH3A1ALDH1A3MAPT
SCHEMBL11216718 0.83 MAPT (0.51) ALDH1A1L3MBTL1MAPTKDM4EMEN1
SCHEMBL11216706 0.83 MAPT (0.51) ALDH1A1L3MBTL1MAPTKDM4EMEN1
SCHEMBL28379902 0.82 ALDH1A1 (0.67) ALDH1A1L3MBTL1ALDH3A1ALDH1A3MAPT
SCHEMBL9192952 0.77 ALDH1A1 (0.61) ALDH1A1L3MBTL1ALDH3A1ALDH1A3MAPT
SCHEMBL21594497 0.77 ALDH1A1 (0.61) ALDH1A1L3MBTL1ALDH3A1ALDH1A3MAPT
SCHEMBL4243407 0.77 ALDH1A1 (0.61) ALDH1A1L3MBTL1ALDH3A1ALDH1A3MAPT
SCHEMBL14283612 0.75 MAPT (0.47) ALDH1A1L3MBTL1MAPTKDM4EMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1052291-B1 Fluorescent stain containing pyrylium salt or its similar salt, detection method of nucleic acid by use of it CANON KK (JP) 2006-10-25 EP disclosed
EP-0684239-B1 A method for detecting a target substance in a sample, utilizing pyrylium compound CANON KK (JP) 2003-12-10 EP disclosed
EP-0643140-B1 Determination of nucleic acid by PCR, measurement of number of microbial cells, genes, or gene-copies by PCR, and measuring-kit employed for the same CANON KK (JP) 2001-10-31 EP disclosed
EP-0603783-B1 Fluorescent stain containing pyrylium salt or its similar salt, detection method of nucleic acid by use of it CANON KK (JP) 2001-09-26 EP disclosed
US-6242477-B1 RADIATING AND KILLING CANCER CELLS CANON KABUSHIKI KAISHA (JP) 2001-06-05 US disclosed
US-6156506-A Method for detecting a target substance in a sample, utilizing pyrylium compound CANON KABUSHIKI KAISHA (JP) 2000-12-05 US disclosed
EP-1052291-A2 Fluorescent stain containing pyrylium salt or its similar salt, detection method of nucleic acid by use of it CANON KABUSHIKI KAISHA (JP) 2000-11-15 EP disclosed
US-6124342-A RADIATION THERAPY TO INDUCE DEATH OF THE CANCER CELLS CANON KK (JP) 2000-09-26 US disclosed
US-6022961-A HYBRIDIZATION PROBE OF SINGLE-STRANDED NUCLEIC ACID HAVING NUCLEOTIDE SEQUENCE COMPLEMENTARY TO TARGET AND WITH COVALENTLY BOUND DYE CANON KABUSHIKI KAISHA (JP) 2000-02-08 US disclosed
US-5670315-A AMPLIFICATION; QUANTITATIVE ANALYSIS CANON KABUSHIKI KAISHA (JP) 1997-09-23 US disclosed
US-5624798-A Detection method of nucleic acid by use of fluorescent pyrylium stain in intercalation into nucleic acids CANON KABUSHIKI KAISHA (JP) 1997-04-29 US disclosed
EP-0684239-A1 A method for detecting a target substance in a sample, utilizing pyrylium compound CANON KABUSHIKI KAISHA (JP) 1995-11-29 EP disclosed
EP-0659407-A1 Pharmaceutical compositions containing pyrylium compounds, pyrylium salts and process for manufacturing a medicament containing the aforesaid compounds CANON KABUSHIKI KAISHA (JP) 1995-06-28 EP disclosed
EP-0643140-A1 Determination of nucleic acid by PCR, measurement of number of microbial cells, genes, or gene-copies by PCR, and measuring-kit employed for the same CANON KABUSHIKI KAISHA (JP) 1995-03-15 EP disclosed
EP-0603783-A1 Fluorescent stain containing pyrylium salt or its similar salt, detection method of nucleic acid by use of it, and fluorescent staining method of biological sample CANON KABUSHIKI KAISHA (JP) 1994-06-29 EP disclosed