Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 6/20 | 0.65 |
| ▸ | RELA | Q04206 | 1/20 | 0.63 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.57 |
| ▸ | CYP2A13 | Q16696 | 1/20 | 0.57 |
| ▸ | SNCA | P37840 | 2/20 | 0.54 |
| ▸ | MAOA | P21397 | 1/20 | 0.51 |
| ▸ | MAOB | P27338 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 4/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.50 |
| ▸ | MAPT | P10636 | 3/20 | 0.50 |
| ▸ | NPC1 | O15118 | 2/20 | 0.50 |
| ▸ | RAB9A | P51151 | 2/20 | 0.50 |
| ▸ | CASP1 | P29466 | 2/20 | 0.50 |
| ▸ | HBB | P68871 | 2/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.50 |
| ▸ | RAD52 | P43351 | 1/20 | 0.49 |
| ▸ | MAT2A | P31153 | 1/20 | 0.49 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.49 |
| ▸ | HSD17B3 | P37058 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7944755 | 1.00 | APP (0.65) | APPRELACYP2A6CYP2A13SNCA | |
| SCHEMBL28347774 | 0.82 | APP (0.65) | APPRELASNCAMAOAMAOB | |
| SCHEMBL7944758 | 0.81 | RELA (0.58) | APPRELACYP2A6CYP2A13SNCA | |
| SCHEMBL5709304 | 0.81 | ALDH1A1 (0.62) | APPMEN1KMT2AMAPTNPC1 | |
| SCHEMBL5709303 | 0.81 | ALDH1A1 (0.62) | APPMEN1KMT2AMAPTNPC1 | |
| SCHEMBL2013090 | 0.81 | CYP2A6 (0.86) | APPRELACYP2A6CYP2A13MEN1 | |
| SCHEMBL2013092 | 0.81 | CYP2A6 (0.86) | APPRELACYP2A6CYP2A13MEN1 | |
| SCHEMBL14895393 | 0.80 | APP (0.67) | APPRELASNCAMAOAMAOB | |
| SCHEMBL2776337 | 0.80 | APP (0.67) | APPRELASNCAMAOAMAOB | |
| SCHEMBL2776332 | 0.80 | APP (0.67) | APPRELASNCAMAOAMAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6242477-B1 | RADIATING AND KILLING CANCER CELLS | CANON KABUSHIKI KAISHA (JP) | 2001-06-05 | — | — | US | disclosed |
| US-6124342-A | RADIATION THERAPY TO INDUCE DEATH OF THE CANCER CELLS | CANON KK (JP) | 2000-09-26 | — | — | US | disclosed |
| EP-0659407-A1 | Pharmaceutical compositions containing pyrylium compounds, pyrylium salts and process for manufacturing a medicament containing the aforesaid compounds | CANON KABUSHIKI KAISHA (JP) | 1995-06-28 | — | — | EP | disclosed |