Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RELA | Q04206 | 1/20 | 0.58 |
| ▸ | APP | P05067 | 6/20 | 0.47 |
| ▸ | RAB9A | P51151 | 3/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | NPC1 | O15118 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | CYP1B1 | Q16678 | 2/20 | 0.45 |
| ▸ | CASP3 | P42574 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.45 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.45 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.45 |
| ▸ | SNCA | P37840 | 1/20 | 0.44 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.43 |
| ▸ | CYP2A13 | Q16696 | 1/20 | 0.43 |
| ▸ | MAOA | P21397 | 1/20 | 0.42 |
| ▸ | MAOB | P27338 | 1/20 | 0.42 |
| ▸ | INSR | P06213 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KLF5 | Q13887 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5709308 | 0.83 | ALDH1A1 (0.52) | RELARAB9AKMT2ANPC1MAPT | |
| SCHEMBL7944752 | 0.81 | APP (0.65) | RELAAPPRAB9AKMT2ANPC1 | |
| SCHEMBL7944755 | 0.81 | APP (0.65) | RELAAPPRAB9AKMT2ANPC1 | |
| SCHEMBL11755707 | 0.80 | RELA (0.61) | RELAAPPRAB9AKMT2ANPC1 | |
| SCHEMBL31166670 | 0.80 | RELA (0.61) | RELAAPPRAB9AKMT2ANPC1 | |
| SCHEMBL10430144 | 0.76 | PTGS2 (0.64) | RELAMAPT | |
| SCHEMBL28000105 | 0.76 | RELA (0.51) | RELAAPPRAB9AKMT2ANPC1 | |
| SCHEMBL10430142 | 0.76 | PTGS2 (0.64) | RELAMAPT | |
| SCHEMBL1557244 | 0.74 | RELA (1.00) | RELAAPPRAB9AKMT2ANPC1 | |
| SCHEMBL1557242 | 0.74 | RELA (1.00) | RELAAPPRAB9AKMT2ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6242477-B1 | RADIATING AND KILLING CANCER CELLS | CANON KABUSHIKI KAISHA (JP) | 2001-06-05 | — | — | US | disclosed |
| US-6124342-A | RADIATION THERAPY TO INDUCE DEATH OF THE CANCER CELLS | CANON KK (JP) | 2000-09-26 | — | — | US | disclosed |
| EP-0659407-A1 | Pharmaceutical compositions containing pyrylium compounds, pyrylium salts and process for manufacturing a medicament containing the aforesaid compounds | CANON KABUSHIKI KAISHA (JP) | 1995-06-28 | — | — | EP | disclosed |