Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 5/20 | 0.46 |
| ▸ | UBE2M | P61081 | 3/20 | 0.46 |
| ▸ | DCUN1D1 | Q96GG9 | 3/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | TMEM97 | Q5BJF2 | 2/20 | 0.43 |
| ▸ | CCR3 | P51677 | 1/20 | 0.43 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.42 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.42 |
| ▸ | ACKR3 | P25106 | 1/20 | 0.42 |
| ▸ | DRD2 | P14416 | 1/20 | 0.42 |
| ▸ | DRD4 | P21917 | 1/20 | 0.42 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | DPP4 | P27487 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5709465 | 0.88 | OPRM1 (0.48) | OPRM1UBE2MDCUN1D1ALDH1A1CHRM2 | |
| SCHEMBL27655096 | 0.83 | ALDH1A1 (0.42) | UBE2MDCUN1D1ALDH1A1TDP1ACKR3 | |
| SCHEMBL5709513 | 0.82 | OPRM1 (0.49) | OPRM1UBE2MDCUN1D1ALDH1A1CHRM2 | |
| SCHEMBL5709506 | 0.81 | SIGMAR1 (0.50) | OPRM1SIGMAR1MEN1KMT2A | |
| SCHEMBL5709507 | 0.80 | OPRM1 (0.52) | OPRM1UBE2MDCUN1D1ALDH1A1CCR3 | |
| SCHEMBL5709432 | 0.76 | OPRM1 (0.55) | OPRM1ALDH1A1CHRM2CHRM3DRD2 | |
| SCHEMBL27655164 | 0.74 | HTR2A (0.46) | ALDH1A1TDP1DRD2DRD4MEN1 | |
| SCHEMBL3150259 | 0.73 | DPP4 (0.47) | OPRM1ALDH1A1TDP1ACKR3DRD2 | |
| SCHEMBL3592324 | 0.73 | ACHE (0.47) | ALDH1A1TDP1CCR3DRD2DRD4 | |
| SCHEMBL5709435 | 0.73 | ACHE (0.60) | OPRM1ALDH1A1CHRM2CHRM3DRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1720550-A1 | DERIVATIVES OF PIPERIDINYLALKYLCARBAMATES, PREPARATION METHOD THEREOF AND USE OF SAME AS FAAH ENZYME INHIBITORS | Sanofi-Aventis (FR) | 2006-11-15 | — | — | EP | disclosed |
| WO-2005089759-A1 | DERIVATIVES OF PIPERIDINYLALKYLCARBAMATES, PREPARATION METHOD THEREOF AND USE OF SAME AS FAAH ENZYME INHIBITORS | SANOFI-AVENTIS (FR) | 2005-09-29 | — | — | WO | disclosed |