Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CACNA1G | O43497 | 1/20 | 0.46 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.43 |
| ▸ | HTR2A | P28223 | 2/20 | 0.43 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.43 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.42 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.41 |
| ▸ | HTR2C | P28335 | 1/20 | 0.41 |
| ▸ | CCR3 | P51677 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3589971 | 0.80 | CACNA1G (0.48) | CACNA1GKCNH2 | |
| SCHEMBL13037096 | 0.80 | CACNA1G (0.43) | CACNA1GKCNH2 | |
| SCHEMBL3589972 | 0.79 | CCR5 (0.50) | CACNA1GSIGMAR1HTR2AGRM2 | |
| SCHEMBL2975081 | 0.78 | CACNA1G (0.43) | CACNA1GHTR2AGRM2KCNH2HTR2C | |
| SCHEMBL2975084 | 0.78 | CACNA1G (0.41) | CACNA1GKCNH2 | |
| SCHEMBL2975087 | 0.74 | CACNA1G (0.41) | CACNA1GSIGMAR1HTR2AGRM2KCNH2 | |
| SCHEMBL5709481 | 0.73 | HTR1A (0.48) | SIGMAR1 | |
| SCHEMBL5709471 | 0.72 | DRD2 (0.56) | SIGMAR1HRH3 | |
| SCHEMBL5709514 | 0.71 | HRH3 (0.53) | SIGMAR1HRH3CCR3 | |
| SCHEMBL5709528 | 0.70 | KDM4E (0.45) | SIGMAR1HTR2AKCNH2HRH3HTR2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1720550-A1 | DERIVATIVES OF PIPERIDINYLALKYLCARBAMATES, PREPARATION METHOD THEREOF AND USE OF SAME AS FAAH ENZYME INHIBITORS | Sanofi-Aventis (FR) | 2006-11-15 | — | — | EP | disclosed |
| WO-2005089759-A1 | DERIVATIVES OF PIPERIDINYLALKYLCARBAMATES, PREPARATION METHOD THEREOF AND USE OF SAME AS FAAH ENZYME INHIBITORS | SANOFI-AVENTIS (FR) | 2005-09-29 | — | — | WO | disclosed |