Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 1/20 | 0.48 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.48 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.46 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.46 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.46 |
| ▸ | DRD4 | P21917 | 1/20 | 0.45 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.44 |
| ▸ | ACHE | P22303 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | PGR | P06401 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.43 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.43 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.43 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.43 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.43 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5709514 | 0.80 | HRH3 (0.53) | HTR1ASLC6A4CARM1PRMT6DRD4 | |
| SCHEMBL2967235 | 0.77 | OPRM1 (0.48) | HTR1ASLC6A4MTNR1ADRD4SIGMAR1 | |
| SCHEMBL3936968 | 0.76 | DRD4 (0.63) | DRD4SIGMAR1ADRA1DADRA1AADRA1B | |
| SCHEMBL5709493 | 0.76 | CARM1 (0.47) | SLC6A4CARM1PRMT6CHRM3 | |
| SCHEMBL3938943 | 0.74 | OPRM1 (0.50) | HTR1ASLC6A4DRD4ACHESIGMAR1 | |
| SCHEMBL3938247 | 0.74 | HTR1A (0.53) | HTR1ASLC6A4DRD4SIGMAR1ADRA1D | |
| SCHEMBL2982820 | 0.74 | HTR1A (0.46) | HTR1ASLC6A4MTNR1ADRD4ACHE | |
| SCHEMBL2982819 | 0.74 | SIGMAR1 (0.43) | HTR1ASLC6A4MTNR1ADRD4ACHE | |
| SCHEMBL2177229 | 0.73 | KMT2A (0.53) | MTNR1AALDH1A1GAAHSD17B10SIGMAR1 | |
| SCHEMBL5709455 | 0.73 | CACNA1G (0.46) | SIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1720550-A1 | DERIVATIVES OF PIPERIDINYLALKYLCARBAMATES, PREPARATION METHOD THEREOF AND USE OF SAME AS FAAH ENZYME INHIBITORS | Sanofi-Aventis (FR) | 2006-11-15 | — | — | EP | disclosed |
| WO-2005089759-A1 | DERIVATIVES OF PIPERIDINYLALKYLCARBAMATES, PREPARATION METHOD THEREOF AND USE OF SAME AS FAAH ENZYME INHIBITORS | SANOFI-AVENTIS (FR) | 2005-09-29 | — | — | WO | disclosed |