Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 1/20 | 0.61 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.54 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.51 |
| ▸ | C5AR1 | P21730 | 1/20 | 0.51 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.50 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.50 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.50 |
| ▸ | KDM1A | O60341 | 2/20 | 0.48 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5709471 | 0.86 | DRD2 (0.56) | DRD2SIGMAR1KCNA3C5AR1CHRM5 | |
| SCHEMBL5709428 | 0.84 | DRD2 (0.54) | DRD2SIGMAR1KCNA3C5AR1CHRM5 | |
| SCHEMBL8971246 | 0.79 | DRD2 (0.59) | DRD2SIGMAR1KCNA3C5AR1KDM1A | |
| SCHEMBL3586725 | 0.78 | DRD2 (0.58) | DRD2SIGMAR1KCNA3C5AR1KDM1A | |
| SCHEMBL3604727 | 0.77 | C5AR1 (0.60) | DRD2SIGMAR1KCNA3C5AR1KMT2A | |
| SCHEMBL3604725 | 0.76 | LTA4H (0.60) | DRD2SIGMAR1KCNA3C5AR1KDM1A | |
| SCHEMBL19479125 | 0.76 | DRD2 (1.00) | DRD2SIGMAR1KMT2A | |
| SCHEMBL6796835 | 0.76 | SIGMAR1 (0.57) | DRD2SIGMAR1KCNA3HRH3 | |
| SCHEMBL20683713 | 0.76 | SIGMAR1 (0.57) | DRD2SIGMAR1KCNA3HRH3 | |
| SCHEMBL6796838 | 0.76 | SIGMAR1 (0.57) | DRD2SIGMAR1KCNA3HRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1720550-A1 | DERIVATIVES OF PIPERIDINYLALKYLCARBAMATES, PREPARATION METHOD THEREOF AND USE OF SAME AS FAAH ENZYME INHIBITORS | Sanofi-Aventis (FR) | 2006-11-15 | — | — | EP | disclosed |
| WO-2005089759-A1 | DERIVATIVES OF PIPERIDINYLALKYLCARBAMATES, PREPARATION METHOD THEREOF AND USE OF SAME AS FAAH ENZYME INHIBITORS | SANOFI-AVENTIS (FR) | 2005-09-29 | — | — | WO | disclosed |