SCHEMBL3604727

SCHEMBL3604727

COc1ccc(CCCN2CCC(N(C)C(=O)O)CC2)cc1

nearest known ligand 0.60

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
C5AR1 P21730 1/20 0.60
OPRM1 P35372 4/20 0.58
CCR5 P51681 2/20 0.57
DRD2 P14416 1/20 0.57
SIGMAR1 Q99720 3/20 0.56
KCNA3 P22001 1/20 0.53
CTSD P07339 1/20 0.51
KMT2A Q03164 1/20 0.50
LTA4H P09960 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2980152 0.82 C5AR1 (0.62) C5AR1OPRM1CCR5DRD2SIGMAR1
SCHEMBL3594347 0.81 OPRM1 (0.58) OPRM1CCR5DRD2SIGMAR1KMT2A
SCHEMBL3586725 0.80 DRD2 (0.58) C5AR1DRD2SIGMAR1KCNA3KMT2A
SCHEMBL3044722 0.79 ALOX5 (0.60) C5AR1OPRM1CCR5DRD2SIGMAR1
SCHEMBL8971246 0.78 DRD2 (0.59) C5AR1OPRM1DRD2SIGMAR1KCNA3
SCHEMBL3604725 0.78 LTA4H (0.60) C5AR1DRD2SIGMAR1KCNA3LTA4H
SCHEMBL3598407 0.78 OPRM1 (0.53) OPRM1DRD2SIGMAR1
SCHEMBL5709503 0.77 DRD2 (0.61) C5AR1DRD2SIGMAR1KCNA3KMT2A
SCHEMBL2980435 0.76 KCNA3 (0.51) C5AR1OPRM1DRD2SIGMAR1KCNA3
SCHEMBL3946392 0.76 CHRM4 (0.62) OPRM1DRD2SIGMAR1KCNA3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1720550-B1 DERIVATIVES OF PIPERIDINYLALKYLCARBAMATES, PREPARATION METHOD THEREOF AND USE OF SAME AS FAAH ENZYME INHIBITORS SANOFI AVENTIS (FR) 2009-04-15 EP claimed
US-20100279998-A1 PIPERIDINYLALKYLCARBAMATE DERIVATIVES, METHODS FOR THEIR PREPARATION AND THE THERAPEUTIC USE THEREOF AS FATTY ACID AMIDO HYDROLASE ENZYME INHIBITORS SANOFI-AVENTIS (FR) 2010-11-04 US disclosed
EP-1720550-B1 DERIVATIVES OF PIPERIDINYLALKYLCARBAMATES, PREPARATION METHOD THEREOF AND USE OF SAME AS FAAH ENZYME INHIBITORS SANOFI AVENTIS (FR) 2009-04-15 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100279998-A1 PIPERIDINYLALKYLCARBAMATE DERIVATIVES, METHODS FOR THEIR PREPARATION AND THE THERAPEUTIC USE THEREOF AS FATTY ACID AMIDO HYDROLASE ENZYME INHIBITORS FAAH, FAAH2, CNR2 C5AR1 1744/4885OPRM1 782/4885CCR5 1522/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.