Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 1/20 | 0.59 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.57 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.55 |
| ▸ | KDM1A | O60341 | 2/20 | 0.54 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.54 |
| ▸ | C5AR1 | P21730 | 1/20 | 0.52 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3604725 | 0.82 | LTA4H (0.60) | DRD2KCNA3SIGMAR1KDM1AHDAC6 | |
| SCHEMBL3590284 | 0.81 | SIGMAR1 (0.60) | SIGMAR1OPRM1 | |
| SCHEMBL3946392 | 0.80 | CHRM4 (0.62) | DRD2KCNA3SIGMAR1KDM1AHDAC6 | |
| SCHEMBL5709503 | 0.79 | DRD2 (0.61) | DRD2KCNA3SIGMAR1KDM1AHDAC6 | |
| SCHEMBL3586725 | 0.79 | DRD2 (0.58) | DRD2KCNA3SIGMAR1KDM1AHDAC6 | |
| SCHEMBL3604727 | 0.78 | C5AR1 (0.60) | DRD2KCNA3SIGMAR1C5AR1OPRM1 | |
| SCHEMBL5709471 | 0.77 | DRD2 (0.56) | DRD2KCNA3SIGMAR1KDM1AHDAC6 | |
| SCHEMBL6796835 | 0.76 | SIGMAR1 (0.57) | DRD2KCNA3SIGMAR1OPRM1 | |
| SCHEMBL6796838 | 0.76 | SIGMAR1 (0.57) | DRD2KCNA3SIGMAR1OPRM1 | |
| SCHEMBL8111284 | 0.76 | HRH3 (0.81) | DRD2SIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0700383-A1 | NOVEL 1-PHENYLALKANONE 5-HT 4? RECEPTOR LIGANDS | SYNTEX (U.S.A.) INC. (US) | 1996-03-13 | — | — | EP | disclosed |