Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | ESR1 | P03372 | 1/20 | 0.41 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.41 |
| ▸ | RAPGEF4 | Q8WZA2 | 3/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | MAOA | P21397 | 1/20 | 0.38 |
| ▸ | MAOB | P27338 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.38 |
| ▸ | CYP2A6 | P11509 | 2/20 | 0.38 |
| ▸ | ESRRA | P11474 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | ELANE | P08246 | 1/20 | 0.37 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.37 |
| ▸ | ABL1 | P00519 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL714974 | 0.80 | ALDH1A1 (0.42) | TDP1TP53RAPGEF4MAPTGAA | |
| SCHEMBL25813777 | 0.80 | MAPT (0.44) | TDP1TP53ESR1ESR2RAPGEF4 | |
| SCHEMBL139182 | 0.77 | ESRRA (0.46) | TDP1TP53MAOAMAOBCYP1A2 | |
| SCHEMBL284409 | 0.77 | ESR2 (0.47) | TDP1TP53ESR1ESR2RAPGEF4 | |
| SCHEMBL30445989 | 0.77 | ESRRA (0.46) | TDP1TP53MAOAMAOBCYP1A2 | |
| SCHEMBL1046094 | 0.77 | ESRRA (0.46) | TDP1TP53MAOAMAOBCYP1A2 | |
| SCHEMBL26529413 | 0.76 | ESR2 (0.47) | TDP1TP53ESR1ESR2RAPGEF4 | |
| SCHEMBL278217 | 0.76 | S1PR4 (0.53) | MAPTMAOBS1PR4ABL1MEN1 | |
| SCHEMBL5551209 | 0.76 | ACHE (0.48) | TP53ESR1ESR2MAPTGAA | |
| SCHEMBL23908222 | 0.76 | TDP1 (0.47) | TDP1ESR2MAPTMAOBALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0888290-B1 | AZULENYL NITRONE SPIN TRAPPING AGENTS, METHODS OF MAKING AND USING SAME | FLORIDA INTERNAT UNIVERSITY (US) | 2006-12-27 | — | — | EP | disclosed |
| EP-0888290-A4 | AZULENYL NITRONE SPIN TRAPPING AGENTS, METHODS OF MAKING AND USING SAME | FLORIDA INTERNAT UNIVERSITY (US) | 2004-08-18 | — | — | EP | disclosed |
| US-6291702-B1 | AS AGENTS FOR TRAPPING AND IDENTIFYING FREE RADICAL SPECIES AND FIND USE AS EFFICIENT ANTIOXIDANTS IN PHYSICOCHEMICAL AND BIOLOGICAL SYSTEMS. | FLORIDA INTERNATIONAL UNIVERSITY | 2001-09-18 | — | — | US | disclosed |
| US-6197825-B1 | EFFECTIVE AGENTS FOR TRAPPING AND IDENTIFYING FREE RADICAL SPECIES AND FIND USE AS EFFICIENT ANTIOXIDANTS IN PHYSICOCHEMICAL AND BIOLOGICAL SYSTEMS. DIAMAGNETIC NITRONE COMPOUND (THE ?SPIN TRAP?) REACTS WITH A TRANSIENT FREE | FLORIDA INTERNATIONAL UNIVERSITY | 2001-03-06 | — | — | US | disclosed |
| US-6083988-A | AZULENYL NITRONES ARE EFFECTIVE AGENTS FOR TRAPPING AND IDENTIFYING FREE RADICALS AND FIND USE AS EFFICIENT ANTIOXIDANT IN PHYSICOCHEMICAL AND BIOLOGICAL SYSTEMS | FLORIDA INTERNATIONAL UNIVERSITY | 2000-07-04 | — | — | US | disclosed |
| EP-0888290-A1 | AZULENYL NITRONE SPIN TRAPPING AGENTS, METHODS OF MAKING AND USING SAME | Florida International University (US) | 1999-01-07 | — | — | EP | disclosed |
| WO-1997019054-A9 | AZULENYL NITRONE SPIN TRAPPING AGENTS, METHODS OF MAKING AND USING SAME | — | 1997-08-07 | — | — | WO | disclosed |
| WO-1997019054-A1 | AZULENYL NITRONE SPIN TRAPPING AGENTS, METHODS OF MAKING AND USING SAME | FLORIDA INTERNATIONAL UNIVERSITY (US) | 1997-05-29 | — | — | WO | disclosed |