Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.48 |
| ▸ | CTSL | P07711 | 1/20 | 0.48 |
| ▸ | CTSS | P25774 | 1/20 | 0.48 |
| ▸ | ACE | P12821 | 2/20 | 0.48 |
| ▸ | PREP | P48147 | 1/20 | 0.47 |
| ▸ | ATM | Q13315 | 1/20 | 0.47 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 6/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 5/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5711352 | 0.86 | PREP (0.57) | DPP4CYP1A2CTSLCTSSACE | |
| SCHEMBL5711449 | 0.85 | DPP4 (0.56) | DPP4ALDH1A1CTSLCTSSACE | |
| SCHEMBL5711369 | 0.85 | CYP3A4 (0.47) | DPP4ALDH1A1CYP1A2CTSLCTSS | |
| SCHEMBL7669206 | 0.84 | DPP4 (0.42) | DPP4ALDH1A1CYP1A2CTSLCTSS | |
| SCHEMBL5711229 | 0.84 | CAPN1 (0.58) | DPP4CTSLCTSSACEPREP | |
| SCHEMBL5711341 | 0.84 | DPP4 (0.55) | DPP4CTSLCTSSACEPREP | |
| SCHEMBL5711367 | 0.83 | ACE (0.48) | DPP4ALDH1A1CYP1A2ACEPREP | |
| SCHEMBL5711384 | 0.82 | CTSK (0.55) | DPP4CTSLCTSS | |
| SCHEMBL18620601 | 0.82 | ACE (0.62) | ALDH1A1CYP1A2CTSLCTSSACE | |
| SCHEMBL20484555 | 0.82 | ACE (0.62) | ALDH1A1CYP1A2CTSLCTSSACE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1103560-B1 | NOVEL THIAZOLIDINE DERIVATIVES | SANTEN PHARMACEUTICAL CO LTD (JP) | 2006-12-27 | — | — | EP | disclosed |
| US-6410576-B1 | ANTIINFLAMMATORY AGENTS; CARDIOVASCULAR DISORDERS | SANTEN PHARMACEUTICAL CO., LTD. (JP) | 2002-06-25 | — | — | US | disclosed |