Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 8/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | PREP | P48147 | 1/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 6/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.41 |
| ▸ | CTSL | P07711 | 1/20 | 0.41 |
| ▸ | CTSS | P25774 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | REN | P00797 | 1/20 | 0.38 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7670975 | 0.90 | DPP4 (0.49) | DPP4CYP3A4PREPTSHRALDH1A1 | |
| SCHEMBL7668101 | 0.89 | PREP (0.48) | DPP4CYP3A4LMNASMN1; SMN2PREP | |
| SCHEMBL7668192 | 0.87 | CAPN1 (0.49) | DPP4CYP3A4PREPCTSLREN | |
| SCHEMBL7665715 | 0.87 | DPP4 (0.47) | DPP4CYP3A4LMNASMN1; SMN2PREP | |
| SCHEMBL7663439 | 0.86 | DPP4 (0.47) | DPP4PREPOPRK1CTSLCTSS | |
| SCHEMBL7669769 | 0.86 | CASP1 (0.43) | DPP4CYP3A4LMNASMN1; SMN2PREP | |
| SCHEMBL7670814 | 0.86 | REN (0.49) | DPP4PREPCTSLCTSSREN | |
| SCHEMBL5711369 | 0.85 | CYP3A4 (0.47) | DPP4CYP3A4LMNASMN1; SMN2PREP | |
| SCHEMBL7658041 | 0.85 | CTSL (0.44) | DPP4CYP3A4LMNAPREPCTSL | |
| SCHEMBL7668437 | 0.84 | DPP4 (0.55) | DPP4PREPCTSLREN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6410576-B1 | ANTIINFLAMMATORY AGENTS; CARDIOVASCULAR DISORDERS | SANTEN PHARMACEUTICAL CO., LTD. (JP) | 2002-06-25 | — | — | US | disclosed |