Sugi Predict

Sugi Predict / Compounds / Pyrimethanil

Pyrimethanil

Pyrimethanil

SCHEMBL302650

CCCOc1nc2ccc(I)cc2c(=O)n1CCC.Cc1cc(C)nc(Nc2ccccc2)n1

nearest known ligand 0.44

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ CDK4 P11802 6/20 0.44
▸ CCND1 P24385 6/20 0.44
▸ CCND2 P30279 6/20 0.44
▸ CCND3 P30281 6/20 0.44
▸ CCNB2 O95067 3/20 0.44
▸ CCNE2 O96020 3/20 0.44
▸ CDK1 P06493 3/20 0.44
▸ FGFR1 P11362 3/20 0.44
▸ CCNB1 P14635 3/20 0.44
▸ CCNA2 P20248 3/20 0.44
▸ FGFR2 P21802 3/20 0.44
▸ FGFR4 P22455 3/20 0.44
▸ FGFR3 P22607 3/20 0.44
▸ CCNE1 P24864 3/20 0.44
▸ CDK2 P24941 3/20 0.44
▸ CCNA1 P78396 3/20 0.44
▸ CCNB3 Q8WWL7 3/20 0.44
▸ CYP1A2 P05177 7/20 0.40
▸ CYP3A4 P08684 5/20 0.40
▸ TSHR P16473 4/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21925 0.85 USP2 (0.47) TSHRLMNAMAPK1USP2MEN1
SCHEMBL8406727 0.84 USP2 (0.46) TSHRLMNAMAPK1USP2MEN1
SCHEMBL8406726 0.83 USP2 (0.45) TSHRLMNAMAPK1USP2MEN1
SCHEMBL5712394 0.78 MTNR1A (0.40) TSHRLMNAUSP2ALDH1A1SMN1; SMN2
SCHEMBL5712356 0.78 MAPK1 (0.45) TSHRLMNAMAPK1USP2MEN1
SCHEMBL5712361 0.74 ADORA2B (0.40) TSHRMAPK1ALDH1A1SMN1; SMN2
SCHEMBL5712352 0.74 PARG (0.42) TSHRLMNAMAPK1USP2MEN1
SCHEMBL5712364 0.74 ALDH1A1 (0.59) TSHRLMNAMAPK1USP2MEN1
SCHEMBL8422870 0.74 USP2 (0.44) TSHRLMNAMAPK1USP2ALDH1A1
SCHEMBL8423120 0.74 USP2 (0.46) TSHRLMNAMAPK1USP2ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20140179518-A1 Pesticidal Mixtures Comprising Cyanosulfoximine Compounds BASF SE (DE) 2014-06-26 — — US claimed
JP-2012500824-A — — 2012-01-12 — — JP claimed
JP-2011527306-A — — 2011-10-27 — — JP claimed
US-20110159107-A1 Pesticidal Mixtures Comprising Isoxazoline Compounds II BASF SE (DE) 2011-06-30 — — US claimed
US-20110160054-A1 Pesticidal Mixtures Comprising Cyanosulfoximine Compounds and Spinetoram BASF SE (DE) 2011-06-30 — — US claimed
EP-2320741-A2 PESTICIDAL MIXTURES COMPRISING CYANOSULFOXIMINE COMPOUNDS AND SPINETORAM BASF SE (DE) 2011-05-18 — — EP claimed
EP-2317856-A1 PESTICIDAL MIXTURES COMPRISING ISOXAZOLINE COMPOUNDS II BASF SE (DE) 2011-05-11 — — EP claimed
US-20110105321-A1 Pesticidal Mixtures Comprising Cyanosulfoximine Compounds BASF SE (DE) 2011-05-05 — — US claimed
EP-2219456-A1 PESTICIDAL MIXTURES COMPRISING CYANOSULFOXIMINE COMPOUNDS BASF SE (DE) 2010-08-25 — — EP claimed
WO-2010023171-A2 PESTICIDAL MIXTURES COMPRISING CYANOSULFOXIMINE COMPOUNDS AND SPINETORAM BASF SE (DE) 2010-03-04 — — WO claimed
WO-2010003877-A1 PESTICIDAL MIXTURES COMPRISING ISOXAZOLINE COMPOUNDS II BASF SE (DE) 2010-01-14 — — WO claimed
WO-2009062905-A1 PESTICIDAL MIXTURES COMPRISING CYANOSULFOXIMINE COMPOUNDS BASF SE (DE) 2009-05-22 — — WO claimed
WO-2009007233-A2 PESTICIDAL MIXTURES COMPRISING SULFONAMIDES AND ONE OR MORE FUNGICIDES BASF SE (DE) 2009-01-15 — — WO claimed
US-20140179518-A1 Pesticidal Mixtures Comprising Cyanosulfoximine Compounds BASF SE (DE) 2014-06-26 — — US disclosed
US-8597688-B2 Pesticidal mixtures comprising isoxazoline compounds II BASF SE (DE) 2013-12-03 — — US disclosed
US-20110160054-A1 Pesticidal Mixtures Comprising Cyanosulfoximine Compounds and Spinetoram BASF SE (DE) 2011-06-30 — — US disclosed
WO-2010023171-A2 PESTICIDAL MIXTURES COMPRISING CYANOSULFOXIMINE COMPOUNDS AND SPINETORAM BASF SE (DE) 2010-03-04 — — WO disclosed
WO-2010003877-A1 PESTICIDAL MIXTURES COMPRISING ISOXAZOLINE COMPOUNDS II BASF SE (DE) 2010-01-14 — — WO disclosed
WO-2009062905-A1 PESTICIDAL MIXTURES COMPRISING CYANOSULFOXIMINE COMPOUNDS BASF SE (DE) 2009-05-22 — — WO disclosed
WO-2009007233-A2 PESTICIDAL MIXTURES COMPRISING SULFONAMIDES AND ONE OR MORE FUNGICIDES BASF SE (DE) 2009-01-15 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110159107-A1 Pesticidal Mixtures Comprising Isoxazoline Compounds II PRDX1, PRDX2, PRDX5 CDK4 1233/4885CCND1 1016/4885CCND2 388/4885
US-20140179518-A1 Pesticidal Mixtures Comprising Cyanosulfoximine Compounds CPN1, SRM, STS CDK4 1303/4885CCND1 203/4885CCND2 87/4885
US-20110105321-A1 Pesticidal Mixtures Comprising Cyanosulfoximine Compounds CPN1, SRM, STS CDK4 1303/4885CCND1 203/4885CCND2 87/4885
US-20110160054-A1 Pesticidal Mixtures Comprising Cyanosulfoximine Compounds and Spinetoram CHRM3, CHRM2, BRS3 CDK4 3923/4885CCND1 4357/4885CCND2 4516/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.