SCHEMBL5712779

SCHEMBL5712779

O=C1C=C(CO)C(=O)C=C1CO

nearest known ligand 0.37

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
STAT3 P40763 1/20 0.37
PIM1 P11309 2/20 0.35
ERBB2 P04626 1/20 0.35
HKDC1 Q2TB90 1/20 0.35
PDPK1 O15530 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3968141 0.84 STAT3 (0.59) STAT3
SCHEMBL10312241 0.79 ERBB2 (0.43) ERBB2HKDC1
SCHEMBL5145016 0.77 MAOA (0.48) PIM1ERBB2HKDC1
SCHEMBL19307962 0.70 MAPT (0.38)
SCHEMBL5712776 0.69 ALOX5 (0.31) HKDC1
SCHEMBL7163646 0.55 TSHR (0.32)
SCHEMBL5712735 0.52 KDM4E (0.31)
SCHEMBL28875633 0.52 KDM4E (0.43)
SCHEMBL672601 0.47 GRIA1 (0.48) PDPK1
SCHEMBL8055881 0.47 TSHR (0.39)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 33 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11561198-B2 Electronic control of the pH of a solution close to an electrode surface ROBERT BOSCH GMBH (DE) 2023-01-24 US disclosed
US-10942146-B2 Electrochemically active agents for pH modulation in biological buffers ROBERT BOSCH GMBH (DE) 2021-03-09 US disclosed
US-20200363371-A1 ELECTRONIC CONTROL OF THE PH OF A SOLUTION CLOSE TO AN ELECTRODE SURFACE ROBERT BOSCH GMBH (DE) 2020-11-19 US disclosed
US-10379080-B2 Electronic control of the pH of a solution close to an electrode surfaces ROBERT BOSCH GMBH (DE) 2019-08-13 US disclosed
US-20190137444-A1 ELECTRONIC CONTROL OF THE PH OF A SOLUTION CLOSE TO AN ELECTRODE SURFACE BOSCH GMBH ROBERT (DE) 2019-05-09 US disclosed
US-10041905-B2 Electrochemically active agents for pH modulation in biological buffers ROBERT BOSCH GMBH (DE) 2018-08-07 US disclosed
US-10041905-B2 Electrochemically active agents for pH modulation in biological buffers ROBERT BOSCH GMBH (DE) 2018-08-07 US disclosed
US-10011549-B2 Electrochemically active agents for pH modulation in biological buffers ROBERT BOSCH GMBH (DE) 2018-07-03 US disclosed
US-10011549-B2 Electrochemically active agents for pH modulation in biological buffers ROBERT BOSCH GMBH (DE) 2018-07-03 US disclosed
US-9910008-B2 Methods for generating pH/ionic concentration gradient near electrode surfaces for modulating biomolecular interactions ROBERT BOSCH GMBH (DE) 2018-03-06 US disclosed
US-20160025671-A1 METHODS FOR GENERATING pH/IONIC CONCENTRATION GRADIENT NEAR ELECTRODE SURFACES FOR MODULATING BIOMOLECULAR INTERACTIONS ROBERT BOSCH GMBH (DE) 2016-01-28 US disclosed
US-20160025671-A1 METHODS FOR GENERATING pH/IONIC CONCENTRATION GRADIENT NEAR ELECTRODE SURFACES FOR MODULATING BIOMOLECULAR INTERACTIONS ROBERT BOSCH GMBH (DE) 2016-01-28 US disclosed
US-20160003763-A1 METHODS FOR GENERATING pH/IONIC CONCENTRATION GRADIENT NEAR ELECTRODE SURFACES FOR MODULATING BIOMOLECULAR INTERACTIONS, AND BUBBLE DETECTION USING ELECTRODES ROBERT BOSCH GMBH (DE) 2016-01-07 US disclosed
US-20160003763-A1 METHODS FOR GENERATING pH/IONIC CONCENTRATION GRADIENT NEAR ELECTRODE SURFACES FOR MODULATING BIOMOLECULAR INTERACTIONS, AND BUBBLE DETECTION USING ELECTRODES ROBERT BOSCH GMBH (DE) 2016-01-07 US disclosed
US-20160003766-A1 METHODS FOR GENERATING pH/IONIC CONCENTRATION GRADIENT NEAR ELECTRODE SURFACES FOR MODULATING BIOMOLECULAR INTERACTIONS ROBERT BOSCH GMBH (DE) 2016-01-07 US disclosed
US-20160003766-A1 METHODS FOR GENERATING pH/IONIC CONCENTRATION GRADIENT NEAR ELECTRODE SURFACES FOR MODULATING BIOMOLECULAR INTERACTIONS ROBERT BOSCH GMBH (DE) 2016-01-07 US disclosed
EP-1436407-B1 AMPEROMETRIC SENSOR DREW SCIENT CO LTD (US) 2006-12-06 EP disclosed
US-20040265940-A1 Amperometer sensor DREW SCIENTIFIC HOLDINGS, INC. 2004-12-30 US disclosed
EP-1436407-A1 AMPEROMETRIC SENSOR DREW SCIENTIFIC LTD. (GB) 2004-07-14 EP disclosed
WO-2003033726-A1 AMPEROMETRIC SENSOR DREW SCIENTIFIC LIMITED (GB) 2003-04-24 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10942146-B2 Electrochemically active agents for pH modulation in biological buffers CA2, PDE7A, CA1 STAT3 884/4885PIM1 2617/4885ERBB2 3973/4885
US-10011549-B2 Electrochemically active agents for pH modulation in biological buffers CA2, PDE7A, CA1 STAT3 884/4885PIM1 2617/4885ERBB2 3973/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.