Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAS2R14 | Q9NYV8 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 3/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.36 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | AR | P10275 | 3/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | HTR2C | P28335 | 1/20 | 0.34 |
| ▸ | HTR6 | P50406 | 1/20 | 0.34 |
| ▸ | ITGAL | P20701 | 1/20 | 0.34 |
| ▸ | FABP4 | P15090 | 1/20 | 0.33 |
| ▸ | ESR1 | P03372 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.33 |
| ▸ | PGR | P06401 | 1/20 | 0.33 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.33 |
| ▸ | PPARG | P37231 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4605316 | 0.78 | AKR1C3 (0.46) | TAS2R14LMNAAKR1C3AKR1C2KDM4E | |
| SCHEMBL4604515 | 0.76 | MAPT (0.49) | TAS2R14LMNAMAPTAKR1C3AKR1C2 | |
| Propionaldehyde SCHEMBL5712970 | 0.76 | TAS2R14 (0.36) | TAS2R14LMNAMAPTAKR1C3AKR1C2 | |
| SCHEMBL4603431 | 0.74 | DTYMK (0.57) | LMNAMAPTAKR1C3AKR1C2HTT | |
| SCHEMBL5712887 | 0.74 | RXRA (0.56) | PPARGPPARA | |
| SCHEMBL8531244 | 0.69 | POLB (0.53) | TAS2R14LMNAMAPTAKR1C3AKR1C2 | |
| SCHEMBL13107182 | 0.69 | MAPT (0.43) | LMNAMAPTAKR1C3AKR1C2HTT | |
| SCHEMBL5886112 | 0.69 | MAPT (0.40) | LMNAMAPTHTTARKDM4E | |
| SCHEMBL11473055 | 0.66 | LMNA (0.47) | LMNAMAPTHTTARKDM4E | |
| SCHEMBL4620059 | 0.64 | MGLL (0.46) | KDM4EPOLBHTR2CHTR6RXFP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1720825-A1 | NEW COMPOUNDS, METHODS FOR THEIR PREPARATION AND USE THEREOF | Active Biotech AB (SE) | 2006-11-15 | — | — | EP | disclosed |
| WO-2005075410-A1 | NEW COMPOUNDS, METHODS FOR THEIR PREPARATION AND USE THEREOF | ACTIVE BIOTECH AB (SE) | 2005-08-18 | — | — | WO | disclosed |