Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.40 |
| ▸ | NSD2 | O96028 | 1/20 | 0.36 |
| ▸ | RBP4 | P02753 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 3/20 | 0.36 |
| ▸ | CA12 | O43570 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | CA4 | P22748 | 1/20 | 0.36 |
| ▸ | CA7 | P43166 | 1/20 | 0.36 |
| ▸ | CA9 | Q16790 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.35 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | P2RY2 | P41231 | 1/20 | 0.34 |
| ▸ | P2RY1 | P47900 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4604515 | 0.73 | MAPT (0.49) | MAPTPOLBKDM4EALDH1A1TDP1 | |
| SCHEMBL28818585 | 0.73 | ALDH1A1 (0.45) | MAPTALDH1A1TDP1SIRT1ICAM1 | |
| SCHEMBL7926405 | 0.72 | ALDH1A1 (0.41) | MAPTNSD2RBP4CA2KDM4E | |
| SCHEMBL29026508 | 0.70 | HTR1A (0.39) | RBP4CA2ALDH1A1TDP1P2RY2 | |
| SCHEMBL28818579 | 0.70 | MMP2 (0.39) | CA2ALDH1A1TDP1SIRT1 | |
| SCHEMBL4603431 | 0.69 | DTYMK (0.57) | MAPTPOLBKDM4EALDH1A1TDP1 | |
| SCHEMBL5712968 | 0.69 | TAS2R14 (0.36) | MAPTPOLBKDM4ELMNAHTT | |
| Propionaldehyde SCHEMBL5712970 | 0.69 | TAS2R14 (0.36) | MAPTNSD2RBP4KDM4ELMNA | |
| SCHEMBL4605316 | 0.69 | AKR1C3 (0.46) | RBP4POLBKDM4EALDH1A1MCL1 | |
| SCHEMBL19599640 | 0.68 | SLC6A9 (0.52) | MAPTNSD2POLBCA12CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7004979-B2 | Dyeing composition comprising at least one diaminopyrazole oxidation base and at least one pyrazolo-azole coupling agent | L'OREAL S.A. (FR) | 2006-02-28 | — | — | US | disclosed |
| US-20040237220-A1 | Dyeing composition comprising a diaminopyrazole-type oxidation base and a pyrazolo-azole coupling agent | L'OREAL S.A. (FR) | 2004-12-02 | — | — | US | disclosed |
| EP-1432391-A1 | DYEING COMPOSITION COMPRISING A DIAMINOPYRAZOLE-TYPE OXIDATION BASE AND A PYRAZOLO-AZOLE COUPLING AGENT | L'OREAL (FR) | 2004-06-30 | — | — | EP | disclosed |
| WO-2003028686-A1 | DYEING COMPOSITION COMPRISING A DIAMINOPYRAZOLE-TYPE OXIDATION BASE AND A PYRAZOLO-AZOLE COUPLING AGENT | L'OREAL (FR) | 2003-04-10 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040237220-A1 | Dyeing composition comprising a diaminopyrazole-type oxidation base and a pyrazolo-azole coupling agent | KRT18, PPOX, NOX5 | MAPT 314/4885HDAC8 2035/4885NSD2 3471/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.