SCHEMBL571346

SCHEMBL571346

NC(=O)c1cccnc1NC(=O)c1cccnc1

nearest known ligand 0.60

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SIRT2 Q8IXJ6 2/20 0.60
LMNA P02545 1/20 0.55
HIF1A Q16665 1/20 0.55
F7 P08709 1/20 0.54
F3 P13726 1/20 0.54
SARM1 Q6SZW1 1/20 0.54
SIRT6 Q8N6T7 1/20 0.54
SIRT1 Q96EB6 1/20 0.54
SIRT3 Q9NTG7 1/20 0.54
SIRT5 Q9NXA8 1/20 0.54
SIRT4 Q9Y6E7 1/20 0.54
ROCK2 O75116 1/20 0.54
ROCK1 Q13464 1/20 0.54
HDAC1 Q13547 2/20 0.52
HDAC3 O15379 1/20 0.52
HDAC2 Q92769 1/20 0.52
HTT P42858 2/20 0.52
HDAC6 Q9UBN7 1/20 0.51
PIM1 P11309 1/20 0.51
PIM3 Q86V86 1/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18640729 0.87 LMNA (0.56) LMNAHIF1AROCK2ROCK1HDAC1
SCHEMBL6542858 0.83 KDM4E (0.60) LMNAHIF1AROCK2ROCK1HTT
SCHEMBL30142618 0.82 HDAC1 (0.67) LMNAHIF1AROCK2ROCK1HDAC1
SCHEMBL21905480 0.82 HDAC1 (0.67) LMNAHIF1AROCK2ROCK1HDAC1
SCHEMBL1233669 0.82 ALDH1A1 (0.59) SIRT2SMN1; SMN2KDM4EALDH1A1HPGD
SCHEMBL7287487 0.81 SIRT2 (0.76) SIRT2LMNAHIF1AF7F3
SCHEMBL28824956 0.80 RAB9A (0.66) HTTL3MBTL1SMN1; SMN2KDM4EALDH1A1
SCHEMBL6643666 0.77 LMNA (0.67) LMNAHIF1AROCK2ROCK1HDAC1
SCHEMBL30932625 0.77 TLR7 (0.56) LMNAHIF1AALDH1A1HSD17B10TDP1
SCHEMBL2714517 0.77 MAPT (0.65) SIRT2LMNAHTTSMN1; SMN2KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-108368493-A Enzymatic system and method for synthesizing nicotinamide mononucleotide and niacin mononucleotide 新南创新私人有限公司 2018-08-03 CN disclosed
EP-2906050-B1 DIETARY COMPOSITIONS COMPRISING CAPSULES OBTAINED BY COACERVATION WITHOUT THE USE OF TOXIC CROSS-LINKING AGENTS SOC D EXPLOITATION DE PRODUITS POUR LES INDUSTRIES CHIMIQUES SEPPIC (FR) 2018-04-25 EP disclosed
CN-104883900-A Dietary composition comprising capsules obtained by coacervation without toxic cross-linking agents SEPPIC SA 2015-09-02 CN disclosed
US-20150230499-A1 DIETARY COMPOSITIONS COMPRISING CAPSULES OBTAINED BY COACERVATION WITHOUT THE USE OF TOXIC CROSS-LINKING AGENTS SOCIETE D'EXPLOITATION DE PRODUITS PUR LES INDUSTRIES CHIMIQUES SEPPIC (FR) 2015-08-20 US disclosed
EP-2906050-A1 DIETARY COMPOSITIONS COMPRISING CAPSULES OBTAINED BY COACERVATION WITHOUT THE USE OF TOXIC CROSS-LINKING AGENTS Societe D Exploitation De Produits Pour Les Industries Chimiques Seppic (FR) 2015-08-19 EP disclosed
US-20130344167-A1 Galenic Composition Suitable for Administration to a Non-Human Animal, Uses Thereof, and Associated Methods VETALIS SARL (FR) 2013-12-26 US disclosed
EP-2646004-A2 GALENIC COMPOSITION SUITABLE FOR ADMINISTRATION TO A NON-HUMAN ANIMAL, USES THEREOF, AND ASSOCIATED METHODS Vetalis Sarl (FR) 2013-10-09 EP disclosed
WO-2012073170-A2 GALENIC COMPOSITION SUITABLE FOR ADMINISTRATION TO A NON-HUMAN ANIMAL, USES THEREOF, AND ASSOCIATED METHODS VETALIS SARL (FR) 2012-06-07 WO disclosed
WO-2012017363-A1 EFFERVESCENT SOLID GALENIC FORMS FOR ANIMALS VETALIS SARL (FR) 2012-02-09 WO disclosed
CN-1668324-A Methods, compositions and growth and differentiation factors for insulin producing cells NOVOCELL INC (US) 2005-09-14 CN disclosed
US-20040259244-A1 Methods, compositions, and growth and differentiation factors for insulin-producing cells BECTON, DICKINSON AND COMPANY, CO-ASSIGNOR 2004-12-23 US disclosed
US-20040132183-A1 Methods and compositions for expanding and differentiating insulin-producing cells NOVOCELL, INC. 2004-07-08 US disclosed
US-6013250-A FOR FINISHING EFFECT AND SUPERIOR PROTECTION AGAINST ENVIRONMENTAL, CHEMICAL, AND GROOMING-ASSOCIATED DAMAGE L'OREAL S. A. (FR) 2000-01-11 US disclosed
US-5681554-A CONTAINING DIVALENT CATION, HYDROLYZED PROTEIN AND A VITAMIN COSMAIR, INC. (US) 1997-10-28 US disclosed