SCHEMBL571503

SCHEMBL571503

CC(C)(C)OC(=O)NC1(C=O)CC1

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CTSK P43235 3/20 0.38
MEN1 O00255 1/20 0.38
MAPK1 P28482 1/20 0.38
KMT2A Q03164 1/20 0.38
CTSL P07711 1/20 0.35
APLNR P35414 1/20 0.34
NFKB1 P19838 1/20 0.33
NFKB2 Q00653 1/20 0.33
RELA Q04206 1/20 0.33
TDP1 Q9NUW8 1/20 0.33
GAA P10253 2/20 0.33
BTK Q06187 1/20 0.33
MAOA P21397 1/20 0.33
MAOB P27338 1/20 0.33
CA1 P00915 1/20 0.33
CA2 P00918 1/20 0.33
CA7 P43166 1/20 0.33
DGAT1 O75907 1/20 0.32
MAPK10 P53779 1/20 0.32
MIF P14174 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL571320 0.93 CTSK (0.36) CTSKMEN1MAPK1KMT2ACTSL
SCHEMBL76972 0.93 CTSK (0.36) CTSKMEN1MAPK1KMT2ACTSL
SCHEMBL8284389 0.91 CTSK (0.36) CTSKMEN1MAPK1KMT2ACTSL
SCHEMBL1666805 0.88 USP2 (0.37) CTSKMEN1MAPK1KMT2ACTSL
SCHEMBL21505983 0.88 MEN1 (0.37) CTSKMEN1MAPK1KMT2ACTSL
SCHEMBL22079845 0.87 HCRTR2 (0.33) CTSKMEN1MAPK1KMT2A
SCHEMBL22380385 0.85 CTSK (0.33) CTSKMEN1MAPK1KMT2ACTSL
SCHEMBL28421186 0.84 USP2 (0.44)
SCHEMBL23007977 0.84 GAA (0.39) CTSKMEN1MAPK1KMT2AAPLNR
SCHEMBL21119394 0.83 CTSK (0.33) CTSKMEN1MAPK1KMT2ACTSL

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 338 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2026085629-A1 SUBSTITUTED HETEROCYCLIC COMPOUNDS, COMPOSITIONS COMPRISING THEM AND USES THEREOF Université de Montréal (CA) 2026-04-30 WO disclosed
US-12612414-B2 Nitrile SUMO inhibitors and uses thereof CIT THERAPEUTICS, INC. (US) 2026-04-28 US disclosed
US-20260069602-A1 COMPOUNDS, COMPOSITIONS, AND METHODS ACONCAGUA BIO INC (US) 2026-03-12 US disclosed
US-20260049054-A1 NOVEL POTASSIUM CHANNEL INHIBITORS SANIONA AS (DK) 2026-02-19 US disclosed
US-20260042788-A1 STAT6 COMPOUNDS GILEAD SCIENCES INC (US) 2026-02-12 US disclosed
US-20250326767-A1 NOVEL BENZOTHIAZOLE DERIVATIVES CARNA BIOSCIENCES, INC. (JP) 2025-10-23 US disclosed
US-12421249-B2 Inhibitors of APOL1 and methods of using same VERTEX PHARMACEUTICALS INCORPORATED (US) 2025-09-23 US disclosed
US-12391644-B2 Potassium channel inhibitors SANIONA A/S (DK) 2025-08-19 US disclosed
EP-3941903-B1 NOVEL POTASSIUM CHANNEL INHIBITORS SANIONA AS (DK) 2025-07-16 EP disclosed
US-20250205219-A1 TARGETED DEGRADATION OF VAV1 MONTE ROSA THERAPEUTICS AG (CH) 2025-06-26 US disclosed
US-5380874-A Pyrrolidine carbamates DAIICHI SEIYAKU CO., LTD. (JP) 1995-01-10 US disclosed
EP-0207420-B1 PYRIDONECARBOXYLIC ACID DERIVATIVES DAIICHI PHARMACEUTICAL CO., LTD. (JP) 1992-05-06 EP disclosed
US-5098912-A Bactericides for grampositive bacteria DAIICHI SEIYAKU CO., LTD. (JP) 1992-03-24 US disclosed
US-4701552-A ARTIFICIAL SWEETENERS GENERAL FOODS CORPORATION (US) 1987-10-20 US disclosed
US-4678675-A Sweetening with L-aminodicarboxylic acid alkenes GENERAL FOODS CORPORATION (US) 1987-07-07 US disclosed
US-4652676-A L-aminodicarboxylic acid alkenes GENERAL FOODS CORPORATION (US) 1987-03-24 US disclosed
EP-0201844-A1 L-Aminodicarboxylic acid alkenes and an edible composition containing same GENERAL FOODS CORPORATION (US) 1986-11-20 EP disclosed
EP-0201077-A1 L-Aminodicarboxylic acid alkanes and an edible composition containing same GENERAL FOODS CORPORATION (US) 1986-11-12 EP disclosed
US-4622232-A L-aminodicarboxylic acid alkanes GENERAL FOODS CORPORATION (US) 1986-11-11 US disclosed
US-4603012-A L-aminodicarboxylic acid alkanes GENERAL FOODS CORPORATION (US) 1986-07-29 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260042788-A1 STAT6 COMPOUNDS STAT6, IL6ST, NFATC1 CTSK 2215/4885MEN1 4198/4885MAPK1 250/4885
US-12421249-B2 Inhibitors of APOL1 and methods of using same APOL1, PNLIP, APOB CTSK 575/4885MEN1 1732/4885MAPK1 1799/4885
US-12391644-B2 Potassium channel inhibitors KCNJ2, KCNN2, KCNN1 CTSK 819/4885MEN1 2574/4885MAPK1 1084/4885
US-20250326767-A1 NOVEL BENZOTHIAZOLE DERIVATIVES DYRK1A, DYRK4, DYRK2 CTSK 77/4885MEN1 3165/4885MAPK1 609/4885
US-12612414-B2 Nitrile SUMO inhibitors and uses thereof SUMO1, SUMO3, PSMB6 CTSK 2087/4885MEN1 3270/4885MAPK1 2568/4885
US-20260049054-A1 NOVEL POTASSIUM CHANNEL INHIBITORS SCN10A, KCNK10, KCNJ2 CTSK 969/4885MEN1 2323/4885MAPK1 765/4885
US-20250205219-A1 TARGETED DEGRADATION OF VAV1 VAV1, KRAS, CBL CTSK 2842/4885MEN1 1386/4885MAPK1 576/4885
US-20260069602-A1 COMPOUNDS, COMPOSITIONS, AND METHODS SCTR, SSTR1, NPY1R CTSK 1920/4885MEN1 465/4885MAPK1 2195/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.