SCHEMBL5715804

SCHEMBL5715804

CCP(c1ccc(F)cc1F)C(F)(F)C(F)(F)F

nearest known ligand 0.31

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.31
RIPK1 Q13546 2/20 0.31
IDO1 P14902 1/20 0.30
AGXT P21549 1/20 0.30
GAA P10253 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5715819 0.77 CNR1 (0.31)
SCHEMBL5716333 0.77 ALDH1A1 (0.34) ALDH1A1
SCHEMBL5716052 0.76 ALDH1A1 (0.37) ALDH1A1IDO1AGXT
SCHEMBL6793750 0.71 GCGR (0.33)
SCHEMBL5715832 0.70 DPP4 (0.30)
SCHEMBL5716457 0.69 ICMT (0.32)
SCHEMBL2544882 0.68 RIPK1 (0.38) ALDH1A1RIPK1IDO1AGXT
SCHEMBL5715980 0.67
SCHEMBL5715807 0.67 CES2 (0.36) ALDH1A1RIPK1IDO1AGXT
SCHEMBL6793057 0.66 ALDH1A1 (0.42) ALDH1A1IDO1AGXT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1661900-A1 Olefin polymerization cocatalysts derived from group-15 cationic compounds and processes using them ExxonMobil Chemical Patents Inc. (US) 2006-05-31 EP disclosed
EP-1252166-B1 OLEFIN POLYMERIZATION COCATALYSTS DERIVED FROM GROUP-15 CATIONIC COMPOUNDS AND PROCESSES USING THEM EXXONMOBIL CHEM PATENTS INC (US) 2005-11-09 EP disclosed