Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DNM1 | Q05193 | 3/20 | 0.34 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.31 |
| ▸ | GPR84 | Q9NQS5 | 2/20 | 0.31 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.30 |
| ▸ | THRA | P10827 | 1/20 | 0.30 |
| ▸ | THRB | P10828 | 1/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5715850 | 1.00 | DNM1 (0.34) | DNM1EPHX2GPR84KCNH2THRA | |
| SCHEMBL5716236 | 0.98 | DNM1 (0.33) | DNM1EPHX2GPR84 | |
| SCHEMBL5715816 | 0.93 | KDM4E (0.34) | DNM1EPHX2KCNH2KDM4ETDP1 | |
| SCHEMBL5716183 | 0.92 | DNM1 (0.31) | DNM1 | |
| SCHEMBL5715888 | 0.85 | CYP3A4 (0.33) | — | |
| SCHEMBL6792443 | 0.85 | ALDH3A1 (0.35) | TDP1 | |
| SCHEMBL5716469 | 0.84 | CYP3A4 (0.35) | — | |
| SCHEMBL5716169 | 0.84 | GPR84 (0.40) | DNM1EPHX2GPR84THRATHRB | |
| SCHEMBL5715707 | 0.84 | — | — | |
| SCHEMBL5715588 | 0.83 | CYP3A4 (0.32) | TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1661900-A1 | Olefin polymerization cocatalysts derived from group-15 cationic compounds and processes using them | ExxonMobil Chemical Patents Inc. (US) | 2006-05-31 | — | — | EP | disclosed |
| EP-1252166-B1 | OLEFIN POLYMERIZATION COCATALYSTS DERIVED FROM GROUP-15 CATIONIC COMPOUNDS AND PROCESSES USING THEM | EXXONMOBIL CHEM PATENTS INC (US) | 2005-11-09 | — | — | EP | disclosed |