SCHEMBL5716544

SCHEMBL5716544

CCCCC(CC)CCP(CCC)c1cc(F)ccc1F

nearest known ligand 0.38

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.38
ALDH1A1 P00352 5/20 0.31
MAPK1 P28482 1/20 0.31
TDP1 Q9NUW8 1/20 0.31
OPRM1 P35372 2/20 0.30
OPRD1 P41143 2/20 0.30
OPRK1 P41145 2/20 0.30
OPRL1 P41146 2/20 0.30
CYP3A4 P08684 2/20 0.30
KCNH2 Q12809 2/20 0.30
TSHR P16473 1/20 0.30
CA2 P00918 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5716057 0.89 LMNA (0.35) LMNAALDH1A1TDP1CYP3A4KCNH2
SCHEMBL5716391 0.85 LMNA (0.38) LMNAALDH1A1MAPK1TDP1CYP3A4
SCHEMBL5716125 0.84 LMNA (0.35) LMNAALDH1A1TDP1CYP3A4KCNH2
SCHEMBL5715614 0.80 ICMT (0.34)
SCHEMBL5715791 0.76 GHSR (0.35) TDP1CYP3A4TSHR
Boric Acid SCHEMBL6799408 0.74
SCHEMBL5715809 0.73 ALDH1A1 (0.31) ALDH1A1
SCHEMBL6795526 0.73 PDE2A (0.32) LMNAALDH1A1MAPK1
SCHEMBL5716524 0.72 ALDH1A1 (0.37) ALDH1A1TDP1CYP3A4TSHRCA2
SCHEMBL5716193 0.72 LMNA (0.30) LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1661900-A1 Olefin polymerization cocatalysts derived from group-15 cationic compounds and processes using them ExxonMobil Chemical Patents Inc. (US) 2006-05-31 EP disclosed
EP-1252166-B1 OLEFIN POLYMERIZATION COCATALYSTS DERIVED FROM GROUP-15 CATIONIC COMPOUNDS AND PROCESSES USING THEM EXXONMOBIL CHEM PATENTS INC (US) 2005-11-09 EP disclosed