SCHEMBL6795526

SCHEMBL6795526

CCCCP(CF)c1cc(F)ccc1F

nearest known ligand 0.36

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
PDE2A O00408 2/20 0.32
HTR7 P34969 1/20 0.32
CA3 P07451 1/20 0.31
CA6 P23280 1/20 0.31
CA5A P35218 1/20 0.31
CA9 Q16790 1/20 0.31
CA14 Q9ULX7 1/20 0.31
CA5B Q9Y2D0 1/20 0.31
ALDH1A1 P00352 1/20 0.30
LMNA P02545 1/20 0.30
GAA P10253 1/20 0.30
MAPT P10636 1/20 0.30
MAPK1 P28482 1/20 0.30
SMN1; SMN2 Q16637 1/20 0.30
ICMT O60725 2/20 0.30
NFE2L2 Q16236 2/20 0.30
GHSR Q92847 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5715791 0.86 GHSR (0.35) PDE2AHTR7CA3CA6CA5A
SCHEMBL5715614 0.83 ICMT (0.34) PDE2AHTR7GAAMAPTSMN1; SMN2
SCHEMBL5715953 0.81 PDE2A (0.33) PDE2AHTR7CA3CA6CA5A
SCHEMBL6793753 0.80 ICMT (0.34) HTR7GAAICMTGHSR
SCHEMBL6792568 0.76 CES2 (0.32) HTR7ALDH1A1ICMTNFE2L2GHSR
SCHEMBL5715633 0.76 HTR7 (0.32) HTR7ALDH1A1ICMTNFE2L2GHSR
SCHEMBL6786630 0.75 GHSR (0.35) PDE2AHTR7GAAICMTGHSR
SCHEMBL5716153 0.75 GHSR (0.35) PDE2AHTR7GAAICMTGHSR
SCHEMBL2544485 0.74 GCGR (0.34) HTR7ALDH1A1ICMTGHSR
SCHEMBL5716544 0.73 LMNA (0.38) ALDH1A1LMNAMAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6822057-B2 OLEFIN POLYMERIZATION CATALYST SYSTEM IS A REACTION PRODUCT OF A METALLOCENES AND A COCATALYST CONTAINING FLUOROARYL SUBSTITUTED SECONDARY AMINE OR PHSOPHINE COMPOUND AND AN ANION CONTAINING GROUP 13 ELEMENT WHICH IS NONCOORDINATIG EXXON MOBIL CHEMICAL PATENTS INC. 2004-11-23 US disclosed
US-6489480-B2 COORDINATION POLYMERIZATION CATALYST FOR ALPHA-OLEFINS EXXONMOBIL CHEMICAL PATENTS INC. 2002-12-03 US disclosed
US-20020115806-A1 Olefin polymerization catalysts derived from Group-15 cationic compounds and processes using them EXXONMOBIL CHEMICAL PATENTS INC. 2002-08-22 US disclosed
US-20020111265-A1 GROUP-15 CATIONIC COMPOUNDS FOR OLEFIN POLYMERIZATION CATALYSTS EXXONMOBIL CHEMICAL PATENTS INC. 2002-08-15 US disclosed