Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OXTR | P30559 | 1/20 | 0.35 |
| ▸ | RIPK1 | Q13546 | 6/20 | 0.34 |
| ▸ | PTPRZ1 | P23471 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.31 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | CNR1 | P21554 | 1/20 | 0.30 |
| ▸ | TDP2 | O95551 | 1/20 | 0.30 |
| ▸ | NSD2 | O96028 | 1/20 | 0.30 |
| ▸ | ABL1 | P00519 | 1/20 | 0.30 |
| ▸ | PLCG1 | P19174 | 1/20 | 0.30 |
| ▸ | CES1 | P23141 | 1/20 | 0.30 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.30 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6002224 | 0.78 | PTPRZ1 (0.32) | RIPK1PTPRZ1ALDH1A1 | |
| SCHEMBL2599561 | 0.73 | RIPK1 (0.35) | RIPK1PTPRZ1ALDH1A1GAA | |
| SCHEMBL6476899 | 0.73 | KDM4E (0.46) | OXTRKDM4ELMNAMAPK1CNR1 | |
| SCHEMBL30528257 | 0.73 | KDM4E (0.46) | OXTRKDM4ELMNAMAPK1CNR1 | |
| SCHEMBL4062075 | 0.70 | HSP90AA1 (0.38) | ALDH1A1KDM4EALOX12LMNAMAPK1 | |
| SCHEMBL5317135 | 0.70 | PTPRZ1 (0.35) | RIPK1PTPRZ1 | |
| SCHEMBL15718171 | 0.70 | OXTR (0.33) | OXTRALDH1A1 | |
| SCHEMBL5593062 | 0.69 | TXNRD1 (0.37) | ALDH1A1KDM4EALOX12LMNAMAPK1 | |
| SCHEMBL29020446 | 0.69 | SLC40A1 (0.38) | KDM4ELMNAMAPK1HTTTDP1 | |
| SCHEMBL27726966 | 0.69 | CA2 (0.40) | OXTRPTPRZ1ALDH1A1LMNAMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1727804-A1 | N1 - ((PYRAZOL-1-YMETHYL) -2-METHYLPHENYL)- PHATALAMIDE DERIVATIVES AND RELATED COMPOUNDS INSECTICIDES | Bayer CropScience Aktiengesellschaft (DE) | 2006-12-06 | — | — | EP | disclosed |
| WO-2005095351-A1 | N1 - ((PYRAZOL-1-YMETHYL) -2-METHYLPHENYL)- PHATALAMIDE DERIVATIVES AND RELATED COMPOUNDS INSECTICIDES | BAYER CROPSCIENCE AG (DE) | 2005-10-13 | — | — | WO | disclosed |