Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCB1 | P08183 | 2/20 | 0.46 |
| ▸ | ABCG2 | Q9UNQ0 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 5/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.44 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 4/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | MAOA | P21397 | 2/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.39 |
| ▸ | TUBB | P07437 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27770682 | 0.82 | ALDH1A1 (0.53) | ABCB1ABCG2KDM4ECYP3A4HSD17B10 | |
| SCHEMBL718719 | 0.81 | ABCG2 (0.61) | ABCB1ABCG2KDM4ECYP3A4HSD17B10 | |
| SCHEMBL28577776 | 0.78 | KDM4E (0.62) | ABCB1ABCG2KDM4ECYP3A4HSD17B10 | |
| SCHEMBL896578 | 0.74 | KDM4E (0.63) | ABCG2KDM4ECYP3A4HSD17B10CYP2C9 | |
| SCHEMBL775094 | 0.74 | ABCG2 (0.60) | ABCB1ABCG2KDM4ECYP3A4HSD17B10 | |
| SCHEMBL10590278 | 0.72 | ALDH1A1 (0.72) | ABCB1ABCG2KDM4ECYP3A4HSD17B10 | |
| SCHEMBL7236286 | 0.71 | MAOA (0.68) | ABCB1ABCG2KDM4ECYP3A4HSD17B10 | |
| SCHEMBL23883097 | 0.71 | CYP2C9 (0.63) | ABCG2KDM4ECYP3A4HSD17B10CYP2C9 | |
| SCHEMBL30049200 | 0.71 | ABCG2 (0.56) | ABCB1ABCG2KDM4ECYP3A4HSD17B10 | |
| SCHEMBL571690 | 0.71 | MAOA (0.48) | KDM4ECYP3A4HSD17B10CYP2C9TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2598150-A2 | COMPOSITIONS FOR PROLIFERATION OF CELLS AND RELATED METHODS | The Hospital For Sick Children (CA) | 2013-06-05 | — | — | EP | disclosed |
| WO-2012018643-A2 | COMPOSITIONS FOR PROLIFERATION OF CELLS AND RELATED METHODS | THE HOSPITAL FOR SICK CHILDREN (CA) | 2012-02-09 | — | — | WO | disclosed |