SCHEMBL918080

SCHEMBL918080

Cc1cc(-c2cccc3c2Cc2ccccc2-3)ccc1O

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TLR8 Q9NR97 2/20 0.48
HSD17B1 P14061 6/20 0.45
HSD17B2 P37059 6/20 0.45
ESR2 Q92731 2/20 0.44
PNMT P11086 1/20 0.44
NPC1 O15118 1/20 0.42
RAB9A P51151 1/20 0.42
APP P05067 1/20 0.41
CYP3A4 P08684 3/20 0.40
CYP2D6 P10635 3/20 0.40
CYP2C19 P33261 3/20 0.40
MCL1 Q07820 1/20 0.40
ESR1 P03372 1/20 0.39
HTR7 P34969 1/20 0.37
HTR2B P41595 1/20 0.37
PIM1 P11309 1/20 0.36
KDM4E B2RXH2 1/20 0.36
ALDH1A1 P00352 1/20 0.36
CYP1A2 P05177 1/20 0.36
MAPT P10636 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28189247 0.89 PNMT (0.45) TLR8PNMTNPC1RAB9AAPP
SCHEMBL5717486 0.87 TLR8 (0.42) TLR8HSD17B1HSD17B2ESR2PNMT
SCHEMBL29921844 0.87 TLR8 (0.42) TLR8HSD17B1HSD17B2ESR2PNMT
SCHEMBL30314491 0.87 TLR8 (0.42) TLR8HSD17B1HSD17B2ESR2PNMT
SCHEMBL21295458 0.86 APP (0.58) PNMTNPC1RAB9AAPPHTR7
SCHEMBL29019038 0.86 PNMT (0.44) PNMTNPC1RAB9AHTR7HTR2B
SCHEMBL5792235 0.84 PNMT (0.46) PNMTNPC1RAB9AHTR7HTR2B
SCHEMBL3366835 0.82 HSD17B1 (0.47) HSD17B1HSD17B2PNMTNPC1RAB9A
SCHEMBL4640228 0.82 ALDH1A1 (0.49) PNMTNPC1RAB9AAPPHTR7
SCHEMBL17574468 0.82 PRKAB2 (0.49) HSD17B1HSD17B2ESR2PNMTNPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1251 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114230779-B Polycarbonate and preparation method and application thereof 万华化学集团股份有限公司 2024-05-03 CN claimed
CN-117327265-B Preparation method of polycarbonate 上海芮澜工程科技有限公司 2024-04-16 CN claimed
CN-117736072-A Synthesis method of 9, 9-bis (4-hydroxy-3-methylphenyl) fluorene 中唯炼焦技术国家工程研究中心有限责任公司 2024-03-22 CN claimed
CN-117510820-A Polycarbonate with heat resistance, yellowing resistance and precipitation resistance as well as preparation method and application thereof 万华化学集团股份有限公司 2024-02-06 CN claimed
CN-117327265-A Preparation method of polycarbonate 上海芮澜工程科技有限公司 2024-01-02 CN claimed
CN-114824396-B Block type fluorenyl anion exchange membrane containing comb-shaped side chain and preparation method thereof 华侨大学 2023-11-21 CN claimed
CN-113999382-B Preparation method of polycarbonate 万华化学集团股份有限公司 2023-07-11 CN claimed
CN-116348529-A Polycarbonate resin composition and circuit molded article for communication device 帝人株式会社 2023-06-27 CN claimed
CN-116144029-A Organosilicon leveling agent, preparation method thereof, black matrix photosensitive resin composition, color filter and liquid crystal display device 阜阳欣奕华材料科技有限公司 2023-05-23 CN claimed
CN-115975164-A Polycarbonate and preparation method and application thereof 万华化学集团股份有限公司 2023-04-18 CN claimed
CN-104603176-A Polyester co-phosphonates FRX POLYMERS INC 2015-05-06 CN claimed
EP-1840167-B1 TRANSPARENT GEL AND CONTACT LENS COMPRISING THE SAME MENICON CO LTD (JP) 2010-10-06 EP claimed
CN-101624442-A Polycarbonate resin and electrophotographic photoreceptor using the same IDEMITSU KOSAN CO 2010-01-13 CN claimed
CN-100448758-C Method for molding polycarbonate resin TEIJIN CHEMICALS LTD (JP) 2009-01-07 CN claimed
EP-1840167-A1 TRANSPARENT GEL AND CONTACT LENS COMPRISING THE SAME MENICON CO., LTD. (JP) 2007-10-03 EP claimed
EP-1097956-B1 Polycarbonat resin MITSUBISHI GAS CHEMICAL CO (JP) 2006-04-12 EP claimed
CN-1625513-A Method for preserving dry polycarbonate resin and wet molding method of the resin TEIJIN CHEMICALS LTD (JP) 2005-06-08 CN claimed
US-20020061997-A1 Polycarbonate resin MITSUBISHI GAS CHEMICAL COMPANY, INC. 2002-05-23 US claimed
EP-1138714-A2 Polycarbonate resin and optical article used the same MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 2001-10-04 EP claimed
EP-1097956-A1 Low endocrine disruptor polycarbonate resin MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 2001-05-09 EP claimed