Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.36 |
| ▸ | MAPT | P10636 | 4/20 | 0.36 |
| ▸ | MEN1 | O00255 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | GAA | P10253 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | MRGPRX4 | Q96LA9 | 3/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | PPARA | Q07869 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 2/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | ABL1 | P00519 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5717907 | 0.90 | MAPT (0.35) | KMT2AMAPTMEN1ALDH1A1GAA | |
| SCHEMBL5717791 | 0.90 | LMNA (0.38) | KMT2AMAPTMEN1ALDH1A1GAA | |
| SCHEMBL5718073 | 0.90 | HSD17B10 (0.36) | KMT2AMAPTMEN1ALDH1A1GAA | |
| SCHEMBL5722552 | 0.90 | MAPK1 (0.36) | KMT2AMAPTMEN1ALDH1A1GAA | |
| SCHEMBL5717908 | 0.89 | ALDH1A1 (0.35) | KMT2AMAPTMEN1ALDH1A1GAA | |
| SCHEMBL5718283 | 0.89 | MRGPRX4 (0.41) | KMT2AMEN1GAAMRGPRX4 | |
| SCHEMBL5722496 | 0.88 | SENP5 (0.35) | KMT2AMAPTMEN1ALDH1A1PKM | |
| SCHEMBL5717876 | 0.87 | THRA (0.37) | KMT2AMAPTMEN1ALDH1A1GAA | |
| SCHEMBL5717977 | 0.86 | MRGPRX4 (0.42) | KMT2AMAPTMEN1MRGPRX4PKM | |
| SCHEMBL5718143 | 0.86 | MRGPRX4 (0.36) | KMT2AMAPTMEN1ALDH1A1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1732533-A1 | THYROID RECEPTOR AGONISTS | KARO BIO AB (SE) | 2006-12-20 | — | — | EP | disclosed |
| WO-2005092317-A1 | THYROID RECEPTOR AGONISTS | KARO BIO AB (SE) | 2005-10-06 | — | — | WO | disclosed |