Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP7 | Q9UHL4 | 3/20 | 0.33 |
| ▸ | DPP4 | P27487 | 2/20 | 0.33 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5718207 | 0.76 | MAPT (0.40) | DPP7 | |
| SCHEMBL5718231 | 0.76 | MAPT (0.40) | DPP7 | |
| SCHEMBL5718243 | 0.73 | HSD17B10 (0.47) | — | |
| SCHEMBL5718355 | 0.71 | HRH3 (0.35) | — | |
| SCHEMBL31492687 | 0.68 | DPP7 (0.35) | DPP7DPP4DPP8 | |
| SCHEMBL29776399 | 0.67 | CA2 (0.42) | — | |
| SCHEMBL23210678 | 0.65 | STING1 (0.32) | — | |
| SCHEMBL6516915 | 0.65 | ALDH1A1 (0.36) | — | |
| SCHEMBL27975884 | 0.64 | DPP7 (0.40) | DPP7DPP4DPP8 | |
| SCHEMBL5718228 | 0.63 | MAPT (0.40) | DPP7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7141560-B2 | Alanine 2,6-dialkoxyphenyl ester derivatives as hypnotics | AKZO NOBEL N.V. (NL) | 2006-11-28 | — | — | US | disclosed |
| EP-1373188-B1 | ALANINE 2,6-DIALKOXYPHENYL ESTER DERIVATIVES AS HYPNOTICS | AKZO NOBEL NV (NL) | 2006-06-07 | — | — | EP | disclosed |
| US-20040059109-A1 | Alanine 2, 6-dialkoxyphenyl ester derivatives as hypnotics | N.V. ORGANON (NL) | 2004-03-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040059109-A1 | Alanine 2, 6-dialkoxyphenyl ester derivatives as hypnotics | OPRM1, OPRD1, OPRK1 | DPP7 2436/4885DPP4 3605/4885DPP8 2338/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.