Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1D | P28221 | 1/20 | 0.34 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.34 |
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 4/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | FPR1 | P21462 | 1/20 | 0.32 |
| ▸ | CRHBP | P24387 | 1/20 | 0.32 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.32 |
| ▸ | GRIA4 | P48058 | 2/20 | 0.32 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.32 |
| ▸ | RECQL | P46063 | 2/20 | 0.31 |
| ▸ | NPC1 | O15118 | 2/20 | 0.31 |
| ▸ | RAB9A | P51151 | 2/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 2/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5718232 | 0.82 | HTR1D (0.37) | HTR1DADRA1ANISCHALDH1A1SMN1; SMN2 | |
| SCHEMBL29534991 | 0.68 | BRD4 (0.34) | ALDH1A1SMN1; SMN2LMNANPC1RAB9A | |
| SCHEMBL1808402 | 0.68 | BRD4 (0.34) | ALDH1A1SMN1; SMN2LMNANPC1RAB9A | |
| SCHEMBL5718215 | 0.67 | ALDH1A1 (0.34) | HTR1DADRA1ANISCHALDH1A1SMN1; SMN2 | |
| SCHEMBL25245248 | 0.64 | PTGS2 (0.33) | ALDH1A1NPSR1HPGDNPC1RAB9A | |
| SCHEMBL4558348 | 0.62 | PTAFR (0.37) | ALDH1A1SMN1; SMN2LMNANPC1RAB9A | |
| SCHEMBL5718383 | 0.62 | ALDH1A1 (0.37) | HTR1DADRA1ANISCHALDH1A1SMN1; SMN2 | |
| SCHEMBL6018296 | 0.62 | MAPK1 (0.37) | ALDH1A1SMN1; SMN2LMNAHPGDCYP2C9 | |
| SCHEMBL25244357 | 0.62 | APP (0.41) | NISCHALDH1A1HPGDKDM4EMAPT | |
| SCHEMBL13477889 | 0.61 | TNF (0.46) | ALDH1A1SMN1; SMN2NPSR1LMNAHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7141637-B2 | Metallocene compounds and process for the preparation of propylene polymers | BASELL POLYOLEFINE GMBH (DE) | 2006-11-28 | — | — | US | disclosed |
| EP-1448578-B1 | METALLOCENE COMPOUNDS AND PROCESS FOR THE PREPARATION OF PROPYLENE POLYMERS | BASELL POLYOLEFINE GMBH (DE) | 2006-07-26 | — | — | EP | disclosed |