Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1D | P28221 | 1/20 | 0.37 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.37 |
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 5/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.35 |
| ▸ | HPGD | P15428 | 3/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | FPR1 | P21462 | 1/20 | 0.34 |
| ▸ | CRHBP | P24387 | 1/20 | 0.34 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | GRIA2 | P42262 | 5/20 | 0.34 |
| ▸ | GRIA4 | P48058 | 5/20 | 0.34 |
| ▸ | RECQL | P46063 | 3/20 | 0.33 |
| ▸ | KIF11 | P52732 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5718324 | 0.82 | HTR1D (0.34) | HTR1DADRA1ANISCHALDH1A1NPSR1 | |
| SCHEMBL25245248 | 0.81 | PTGS2 (0.33) | ALDH1A1NPSR1HPGDKDM4ENPC1 | |
| SCHEMBL1824700 | 0.80 | MAPK1 (0.38) | ALDH1A1SMN1; SMN2HPGDLMNACYP2C9 | |
| SCHEMBL25244357 | 0.78 | APP (0.41) | NISCHALDH1A1HPGDKDM4EMAPT | |
| SCHEMBL5718215 | 0.77 | ALDH1A1 (0.34) | HTR1DADRA1ANISCHALDH1A1NPSR1 | |
| SCHEMBL25289822 | 0.73 | IKBKB (0.38) | NISCHALDH1A1NPSR1SMN1; SMN2HPGD | |
| SCHEMBL1024342 | 0.72 | TSHR (0.34) | HTR1DADRA1ANISCHALDH1A1HPGD | |
| SCHEMBL31451213 | 0.70 | FGF23 (0.35) | TSHRKDM4EKIF11 | |
| SCHEMBL690593 | 0.68 | TSHR (0.36) | HTR1DADRA1ANISCHALDH1A1SMN1; SMN2 | |
| SCHEMBL1807786 | 0.67 | BRD4 (0.36) | HTR1DADRA1ANISCHALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116410238-A | Sulfur-containing chiral bridged metallocene compound, and preparation and application thereof | 中国石油天然气股份有限公司 | 2023-07-11 | — | — | CN | disclosed |
| WO-2023124996-A1 | SULFUR-CONTAINING CHIRAL BRIDGED METALLOECENE COMPOUND, PREPARATION THEREOF, AND APPLICATION | 中国石油天然气股份有限公司 | 2023-07-06 | — | — | WO | disclosed |
| US-7141637-B2 | Metallocene compounds and process for the preparation of propylene polymers | BASELL POLYOLEFINE GMBH (DE) | 2006-11-28 | — | — | US | disclosed |
| EP-1448578-B1 | METALLOCENE COMPOUNDS AND PROCESS FOR THE PREPARATION OF PROPYLENE POLYMERS | BASELL POLYOLEFINE GMBH (DE) | 2006-07-26 | — | — | EP | disclosed |
| US-20050010058-A1 | Such as {Dimethyl-silyl-(5-isopropyl-2-methyl-3-phenyl-cyclopento[2,3-b]thiophen-6-yl)-(2-methyl-4-phenyl-[3a,4-dihydro]azulen-1-yl)}ZrCl2 catalyst for homo or copolymerization of propylene | EXXONMOBIL CHEMICAL PATENTS INC. | 2005-01-13 | — | — | US | disclosed |
| EP-1448578-A1 | METALLOCENE COMPOUNDS AND PROCESS FOR THE PREPARATION OF PROPYLENE POLYMERS | Basell Polyolefine GmbH (DE) | 2004-08-25 | — | — | EP | disclosed |
| WO-2003045964-A1 | METALLOCENE COMPOUNDS AND PROCESS FOR THE PREPARATION OF PROPYLENE POLYMERS | BASELL POLYOLEFINE GMBH (DE) | 2003-06-05 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050010058-A1 | Such as {Dimethyl-silyl-(5-isopropyl-2-methyl-3-phenyl-cyclopento[2,3-b]thiophen-6-yl)-(2-methyl-4-phenyl-[3a,4-dihydro]azulen-1-yl)}ZrCl2 catalyst for homo or copolymerization of propylene | CHRM1, YWHAZ, PYM1 | HTR1D 287/4885ADRA1A 1291/4885NISCH 4726/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.