Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Diethylamine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BID | P55957 | 3/20 | 0.48 |
| ▸ | MCL1 | Q07820 | 3/20 | 0.48 |
| ▸ | BCL2L1 | Q07817 | 2/20 | 0.48 |
| ▸ | BAK1 | Q16611 | 2/20 | 0.48 |
| ▸ | KAT8 | Q9H7Z6 | 2/20 | 0.48 |
| ▸ | SAE1 | Q9UBE0 | 2/20 | 0.48 |
| ▸ | NAAA | Q02083 | 1/20 | 0.48 |
| ▸ | PPARG | P37231 | 1/20 | 0.48 |
| ▸ | PPARA | Q07869 | 1/20 | 0.48 |
| ▸ | EP300 | Q09472 | 1/20 | 0.48 |
| ▸ | KAT2A | Q92830 | 1/20 | 0.48 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.48 |
| ▸ | KAT5 | Q92993 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 3/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | MMP2 | P08253 | 2/20 | 0.43 |
| ▸ | F7 | P08709 | 2/20 | 0.43 |
| ▸ | F3 | P13726 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL570967 | 0.94 | BID (0.54) | BIDMCL1BCL2L1BAK1KAT8 | |
| SCHEMBL30656414 | 0.85 | TSHR (0.53) | BIDMCL1BCL2L1BAK1KAT8 | |
| Emylcamate SCHEMBL29074632 | 0.81 | BID (0.42) | BIDMCL1BCL2L1BAK1KAT8 | |
| SCHEMBL8512469 | 0.81 | TSHR (0.51) | LMNATSHRHSD17B10ALDH1A1THRA | |
| SCHEMBL1790208 | 0.80 | TSHR (0.48) | BIDMCL1BCL2L1BAK1KAT8 | |
| SCHEMBL9578113 | 0.80 | TSHR (0.50) | BIDMCL1BCL2L1BAK1KAT8 | |
| SCHEMBL3290584 | 0.80 | BID (0.48) | BIDMCL1BCL2L1BAK1KAT8 | |
| SCHEMBL29054012 | 0.80 | PLK1 (0.43) | BIDMCL1BCL2L1BAK1KAT8 | |
| SCHEMBL29148965 | 0.80 | ALDH1A1 (0.62) | BIDMCL1BCL2L1BAK1KAT8 | |
| SCHEMBL11552750 | 0.80 | ALDH1A1 (0.62) | BIDMCL1BCL2L1BAK1KAT8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 163 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3600224-B1 | SKIN CARE COMPOSITIONS COMPRISING A TERPOLYMER, PROCESS FOR PREPARING THE SAME AND METHOD OF USE THEREOF | ISP INVESTMENTS LLC (US) | 2026-05-06 | — | — | EP | claimed |
| CN-119970593-A | Sun-screening composition, application thereof and skin care product | 东烽化学(杭州)有限公司广州分公司 | 2025-05-13 | — | — | CN | claimed |
| CN-119523833-A | Collagen microsphere ergothioneine compound, multifunctional high-efficiency broad-spectrum sun-screening composition containing compound and preparation method | 南京天纵易康生物科技股份有限公司 | 2025-02-28 | — | — | CN | claimed |
| US-12214067-B2 | Oil-in-water emulsion sunscreen composition | ISP INVESTMENTS INC. (US) | 2025-02-04 | — | — | US | claimed |
| US-20220387290-A1 | SUNSCREEN COMPOSITIONS AND METHOD OF USE THEREOF | ISP INVESTMENTS LLC (US) | 2022-12-08 | — | — | US | claimed |
| WO-2022214187-A1 | AN O/W EMULSION BASE AND EMULSIONS COMPRISING THE SAME | SYMRISE AG (DE) | 2022-10-13 | — | — | WO | claimed |
| US-20220125701-A1 | SKIN CARE COMPOSITIONS COMPRISING A TERPOLYMER, PROCESS FOR PREPARING THE SAME AND METHOD OF USE THEREOF | ISP INVESTMENTS LLC (US) | 2022-04-28 | — | — | US | claimed |
| EP-3946642-A1 | SUNSCREEN COMPOSITIONS AND METHOD OF USE THEREOF | ISP Investments LLC (US) | 2022-02-09 | — | — | EP | claimed |
| US-20210338539-A1 | LAMELLAR GEL BASED PERSONAL CARE COMPOSITIONS, PROCESS FOR PREPARING THE SAME AND METHOD OF USE THEREOF | ISP INVESTMENTS LLC | 2021-11-04 | — | — | US | claimed |
| EP-2701670-B1 | CLEAR WET SUN-CARE SPRAYS AND GELS | ISP INVESTMENTS LLC (US) | 2021-10-20 | — | — | EP | claimed |
| EP-3099284-A1 | OIL-IN-WATER EMULSION SUNSCREEN COMPOSITION | ISP Investments Inc. (US) | 2016-12-07 | — | — | EP | claimed |
| EP-2257266-B1 | COMPOSITIONS DESIGNED TO PREVENT/PROTECT AGAINST PHOTOALLERGIC AND PHOTOTOXIC SKIN REACTIONS | BRAGUTI LODOVICO GIANLUCA (IT) | 2016-03-16 | — | — | EP | claimed |
| WO-2015116899-A1 | OIL-IN -WATER EMULSION SUNSCREEN COMPOSITION | ISP INVESTMENTS INC. (US) | 2015-08-06 | — | — | WO | claimed |
| US-8673272-B2 | Ultraviolet-absorbing compounds | ISP INVESTMENTS INC. (US) | 2014-03-18 | — | — | US | claimed |
| EP-2701670-A1 | CLEAR WET SPRAYS AND GELS | Isp Investments Inc. (US) | 2014-03-05 | — | — | EP | claimed |
| US-20140030198-A1 | CLEAR WET SPRAYS AND GELS | ISP INVESTMENT INC. (US) | 2014-01-30 | — | — | US | claimed |
| WO-2012149355-A1 | CLEAR WET SPRAYS AND GELS | ISP INVESTMENTS INC. (US) | 2012-11-01 | — | — | WO | claimed |
| US-20110020251-A1 | Ultraviolet-Absorbing Compounds | AVOCA LLC | 2011-01-27 | — | — | US | claimed |
| EP-2257266-A2 | COMPOSITIONS DESIGNED TO PREVENT/PROTECT AGAINST PHOTOALLERGIC AND PHOTOTOXIC SKIN REACTIONS | Braguti, Lodovico Gianluca (IT) | 2010-12-08 | — | — | EP | claimed |
| WO-2009129904-A2 | COMPOSITIONS DESIGNED TO PREVENT/PROTECT AGAINST PHOTOALLERGIC AND PHOTOTOXIC SKIN REACTIONS | BRAGUTI LODOVICO GIANLUCA (IT) | 2009-10-29 | — | — | WO | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110020251-A1 | Ultraviolet-Absorbing Compounds | UFM1, UHRF1, CUTA | BID 2038/4885MCL1 3537/4885BCL2L1 3512/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.