SCHEMBL3290584

SCHEMBL3290584

CCCCCCc1ccccc1C(=O)OC(=O)c1cccc(O)c1N(CC)CC

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
BID P55957 6/20 0.48
MCL1 Q07820 6/20 0.48
BCL2L1 Q07817 5/20 0.48
BAK1 Q16611 5/20 0.48
KAT8 Q9H7Z6 3/20 0.48
SAE1 Q9UBE0 2/20 0.48
EP300 Q09472 2/20 0.48
KAT5 Q92993 2/20 0.48
PPARA Q07869 2/20 0.48
PPARG P37231 1/20 0.48
KAT2A Q92830 1/20 0.48
KAT2B Q92831 1/20 0.48
F7 P08709 3/20 0.43
F3 P13726 3/20 0.43
MMP2 P08253 2/20 0.43
KDM4E B2RXH2 1/20 0.43
MAPT P10636 1/20 0.43
ALOX15 P16050 1/20 0.43
ECE1 P42892 1/20 0.43
SGMS1 Q86VZ5 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL570967 0.85 BID (0.54) BIDMCL1BCL2L1BAK1KAT8
SCHEMBL825447 0.84 BID (0.42) BIDMCL1BCL2L1BAK1KAT8
SCHEMBL28962198 0.83 TSHR (0.43) BIDMCL1BCL2L1BAK1KAT8
SCHEMBL30656414 0.82 TSHR (0.53) BIDMCL1BCL2L1BAK1KAT8
SCHEMBL27756068 0.82 MEN1 (0.51) BIDMCL1BCL2L1BAK1KAT8
Diethylamine SCHEMBL571942 0.80 BID (0.48) BIDMCL1BCL2L1BAK1KAT8
SCHEMBL2492661 0.79 TSHR (0.62) MMP2KDM4EHSD17B10TSHRALDH1A1
SCHEMBL8512469 0.78 TSHR (0.51) HSD17B10TSHRALDH1A1LMNA
SCHEMBL22638969 0.78 TSHR (0.46) BIDMCL1BCL2L1BAK1KAT8
SCHEMBL1790208 0.77 TSHR (0.48) BIDMCL1BCL2L1BAK1KAT8

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2775997-B1 COSMETIC AND DERMATOLOGICAL PHOTOPROTECTIVE PREPARATION WITH IMPROVED WATER RESISTANCE BEIERSDORF AG (DE) 2019-08-07 EP claimed
US-20140140940-A1 Cosmetic And Dermatological Photoprotective Preparation With Improved Water Resistance BEIERSDORF AG (DE) 2014-05-22 US claimed
US-20240091730-A1 METHOD FOR STABILIZING EFFECTIVE INGREDIENT BY USING MINERAL MATERIAL LG HOUSEHOLD & HEALTH CARE LTD. (KR) 2024-03-21 US disclosed
US-20230002706-A1 NATURALLY DEGRADABLE MICROCAPSULES AND A METHOD OF PREPARING THE SAME LG HOUSEHOLD & HEALTH CARE LTD. (KR) 2023-01-05 US disclosed
WO-2022239842-A1 SKIN EXTERNAL AGENT 花王株式会社 2022-11-17 WO disclosed
EP-4056262-A1 BIODEGRADABLE MICROCAPSULE AND METHOD FOR MANUFACTURING SAME LG Household & Health Care Ltd. (KR) 2022-09-14 EP disclosed
WO-2022146114-A1 METHOD FOR STABILIZING EFFECTIVE INGREDIENT BY USING MINERAL MATERIAL 주식회사 엘지생활건강 2022-07-07 WO disclosed
US-11044931-B2 Low molecular weight modulators of the cold menthol receptor TRPM8 and use thereof BASF SE (DE) 2021-06-29 US disclosed
US-20190350239-A1 LOW MOLECULAR WEIGHT MODULATORS OF THE COLD MENTHOL RECEPTOR TRPM8 AND USE THEREOF BASF SE (DE) 2019-11-21 US disclosed
US-10398159-B2 Low molecular weight modulators of the cold menthol receptor TRPM8 and use thereof BASF SE (DE) 2019-09-03 US disclosed
US-20170265510-A1 LOW MOLECULAR WEIGHT MODULATORS OF THE COLD MENTHOL RECEPTOR TRPM8 AND USE THEREOF BASF SE (DE) 2017-09-21 US disclosed
US-20100135939-A1 UV LIGHT-PROTECTIVE AGENT BASED ON MIXED INORGANIC-ORGANIC SYSTEMS BASF SE (DE) 2010-06-03 US disclosed
US-7727948-B2 Mixture, comprising a surfactant and a cosurfactant that is an amphiphilic polymer BASF SE (DE) 2010-06-01 US disclosed
US-20100015070-A1 USE OF NATURAL, RECOMBINANT AND SYNTHETIC RESILINS IN COSMETICS BASF SE (DE) 2010-01-21 US disclosed
US-20090156485-A1 METHOD FOR COUPLING KERATIN-BINDING POLYPEPTIDES WITH EFFECTOR MOLECULES WHICH SUPPORT CARBOXYLIC GROUPS OR SULFONIC ACID GROUPS BASE SE (DE) 2009-06-18 US disclosed
US-20090136433-A1 Use of Hydrophobin-Polypeptides and Conjugates From Hydrophobin-Polypeptides Having Active and Effect Agents and the Production Thereof and Use Thereof In the Cosmetic Industry BASF AKTIENGESELLSCHAFT (DE) 2009-05-28 US disclosed
US-20090099075-A1 Chimeric Keratin-Binding Effector Proteins BASF SE (DE) 2009-04-16 US disclosed
US-20090098076-A1 Method For the Production of a Keratin-Binding Effector Molecule BASF SE (DE) 2009-04-16 US disclosed
US-20070060495-A1 Mixture, comprising a surfactant and a cosurfactant BASF AKTIENGESELLSCHAFT (DE) 2007-03-15 US disclosed
WO-2005048970-A1 USE OF LIGNANS IN COSMETIC OR DERMATOLOGICAL PREPARATIONS BASF AKTIENGESELLSCHAFT (DE) 2005-06-02 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (9 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170265510-A1 LOW MOLECULAR WEIGHT MODULATORS OF THE COLD MENTHOL RECEPTOR TRPM8 AND USE THEREOF TRPM8, TRPM7, TRPM2 BID 515/4885MCL1 3039/4885BCL2L1 2901/4885
US-20090156485-A1 METHOD FOR COUPLING KERATIN-BINDING POLYPEPTIDES WITH EFFECTOR MOLECULES WHICH SUPPORT CARBOXYLIC GROUPS OR SULFONIC ACID GROUPS KRT18, KRTCAP2, CUTA BID 566/4885MCL1 4087/4885BCL2L1 3381/4885
US-20090136433-A1 Use of Hydrophobin-Polypeptides and Conjugates From Hydrophobin-Polypeptides Having Active and Effect Agents and the Production Thereof and Use Thereof In the Cosmetic Industry KRT18, F12, XPA BID 1858/4885MCL1 3238/4885BCL2L1 2262/4885
US-20100135939-A1 UV LIGHT-PROTECTIVE AGENT BASED ON MIXED INORGANIC-ORGANIC SYSTEMS ERCC1, ERCC4, SOD1 BID 3704/4885MCL1 2061/4885BCL2L1 1737/4885
US-11044931-B2 Low molecular weight modulators of the cold menthol receptor TRPM8 and use thereof TRPM8, TRPM7, TRPM2 BID 515/4885MCL1 3039/4885BCL2L1 2901/4885
US-10398159-B2 Low molecular weight modulators of the cold menthol receptor TRPM8 and use thereof TRPM8, TRPM7, TRPM2 BID 515/4885MCL1 3039/4885BCL2L1 2901/4885
US-20190350239-A1 LOW MOLECULAR WEIGHT MODULATORS OF THE COLD MENTHOL RECEPTOR TRPM8 AND USE THEREOF TRPM8, TRPM7, TRPM2 BID 515/4885MCL1 3039/4885BCL2L1 2901/4885
US-20090099075-A1 Chimeric Keratin-Binding Effector Proteins KRT18, KRTCAP2, CKAP4 BID 239/4885MCL1 1765/4885BCL2L1 2272/4885
US-20090098076-A1 Method For the Production of a Keratin-Binding Effector Molecule KRT18, KRTCAP2, CUTA BID 374/4885MCL1 2908/4885BCL2L1 1972/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.