Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.35 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7203762 | 0.74 | TSHR (0.46) | TSHRKDM4ELMNAGAAHPGD | |
| SCHEMBL85862 | 0.74 | TSHR (0.46) | TSHRKDM4ELMNAGAAHPGD | |
| SCHEMBL7209322 | 0.74 | TSHR (0.46) | TSHRKDM4ELMNAGAAHPGD | |
| SCHEMBL5720117 | 0.72 | NLRP3 (0.49) | TSHRKDM4EHTTALDH1A1CYP2C19 | |
| SCHEMBL5720274 | 0.71 | TRPM8 (0.46) | KDM4ELMNAGAAALDH1A1SMN1; SMN2 | |
| SCHEMBL5719777 | 0.68 | PPM1B (0.46) | TSHRLMNAGAAALDH1A1MAPT | |
| SCHEMBL16402657 | 0.68 | PPM1B (0.46) | TSHRLMNAGAAALDH1A1MAPT | |
| SCHEMBL85522 | 0.68 | PPM1B (0.46) | TSHRLMNAGAAALDH1A1MAPT | |
| SCHEMBL8706315 | 0.67 | TSHR (0.47) | TSHRKDM4ENPSR1LMNAGAA | |
| SCHEMBL17145410 | 0.66 | TSHR (0.42) | TSHRKDM4ELMNAGAAHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1668007-A1 | DIOXOLANE DERIVATIVES AS CELL ADHESION INHIBITORS | Ranbaxy Laboratories Limited (IN) | 2006-06-14 | — | — | EP | disclosed |
| WO-2005026163-A1 | DIOXOLANE DERIVATIVES AS CELL ADHESION INHIBITORS | RANBAXY LABORATORIES LIMITED (IN) | 2005-03-24 | — | — | WO | disclosed |