Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX3 | P56373 | 6/20 | 0.52 |
| ▸ | P2RX2 | Q9UBL9 | 4/20 | 0.51 |
| ▸ | RNASEL | Q05823 | 3/20 | 0.50 |
| ▸ | P2RY1 | P47900 | 5/20 | 0.49 |
| ▸ | P2RX4 | Q99571 | 3/20 | 0.49 |
| ▸ | P2RX1 | P51575 | 2/20 | 0.49 |
| ▸ | ENPP1 | P22413 | 2/20 | 0.49 |
| ▸ | P2RY6 | Q15077 | 2/20 | 0.49 |
| ▸ | GPR17 | Q13304 | 2/20 | 0.49 |
| ▸ | P2RY11 | Q96G91 | 1/20 | 0.49 |
| ▸ | P2RY2 | P41231 | 4/20 | 0.49 |
| ▸ | SRC | P12931 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | P2RY12 | Q9H244 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2919342 | 0.92 | ATIC (0.49) | P2RY1P2RY11P2RY2SRCSMN1; SMN2 | |
| SCHEMBL19458230 | 0.89 | POLB (0.45) | P2RX3P2RX2RNASELP2RY1P2RX1 | |
| SCHEMBL10769449 | 0.84 | P2RX3 (0.53) | P2RX3P2RX2RNASELP2RY1P2RX4 | |
| SCHEMBL11884609 | 0.83 | P2RY2 (0.45) | P2RX3P2RY2 | |
| SCHEMBL625829 | 0.81 | P2RY1 (0.57) | P2RX3P2RX2RNASELP2RY1P2RX4 | |
| SCHEMBL1429148 | 0.80 | ADA (0.46) | ALDH1A1SMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL5928106 | 0.80 | ADA (0.45) | ALDH1A1SMN1; SMN2 | |
| SCHEMBL11884671 | 0.77 | ADA (0.34) | ALDH1A1SMN1; SMN2 | |
| SCHEMBL8028076 | 0.76 | P2RX3 (0.48) | P2RX3P2RX2RNASELP2RY1P2RX4 | |
| SCHEMBL4377679 | 0.76 | RNASEL (0.51) | P2RX3P2RX2RNASELP2RY1P2RX4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6703376-B2 | ADMINISTERING TO THE AIRWAYS OF THE PATIENT A URIDINE PHOSPHATE SUCH AS URIDINE 5'TRIPHOSPHATE OR DI(URIDINE5') TETRAPHOSPHATE FOR PROMOTING DRAINAGE OF MUCOUS SECRETIONS IN THE CONGESTED AIRWAYS OF A BEDRIDDEN/IMMOBILIZED PATIENT | INSPIRE PHARMACEUTICALS, INC. | 2004-03-09 | — | — | US | claimed |
| US-20020155150-A1 | USE OF URIDINE TRIPHOSPHATES AND RELATED COMPOUNDS FOR THE PREVENTION AND TREATMENT OF PNEUMONIA IN IMMOBILIZED PATIENTS | INSPIRE PHARMACEUTICALS, INC. | 2002-10-24 | — | — | US | claimed |
| EP-0889728-B1 | METHOD OF TREATING CILIARY DYSKINESIA WITH URIDINE TRIPHOSPHATES AND RELATED COMPOUNDS | INSPIRE PHARMACEUTICALS INC (US) | 2006-08-09 | — | — | EP | disclosed |
| US-6703376-B2 | ADMINISTERING TO THE AIRWAYS OF THE PATIENT A URIDINE PHOSPHATE SUCH AS URIDINE 5'TRIPHOSPHATE OR DI(URIDINE5') TETRAPHOSPHATE FOR PROMOTING DRAINAGE OF MUCOUS SECRETIONS IN THE CONGESTED AIRWAYS OF A BEDRIDDEN/IMMOBILIZED PATIENT | INSPIRE PHARMACEUTICALS, INC. | 2004-03-09 | — | — | US | disclosed |
| US-20020155150-A1 | USE OF URIDINE TRIPHOSPHATES AND RELATED COMPOUNDS FOR THE PREVENTION AND TREATMENT OF PNEUMONIA IN IMMOBILIZED PATIENTS | INSPIRE PHARMACEUTICALS, INC. | 2002-10-24 | — | — | US | disclosed |
| US-6420347-B1 | Method of treating ciliary dyskinesia with uridine triphosphates and related compounds | INSPIRE PHARMACEUTICALS, INC. | 2002-07-16 | — | — | US | disclosed |
| EP-0938322-A2 | USE OF URIDINE TRIPHOSPHATES AND RELATED COMPOUNDS FOR THE PREVENTION AND TREATMENT OF PNEUMONIA IN IMMOBILIZED PATIENTS | Inspire Pharmaceuticals, Inc. (US) | 1999-09-01 | — | — | EP | disclosed |
| EP-0889728-A2 | METHOD OF TREATING CILIARY DYSKINESIA WITH URIDINE TRIPHOSPHATES AND RELATED COMPOUNDS | Inspire Pharmaceuticals, Inc. (US) | 1999-01-13 | — | — | EP | disclosed |
| US-5763447-A | Method of preventing or treating pneumonia in immobilized patients with uridine triphosphates and related compounds | INSPIRE PHARMACEUTICALS (US) | 1998-06-09 | — | — | US | disclosed |
| WO-1997035591-A9 | METHOD OF TREATING CILIARY DYSKINESIA WITH URIDINE TRIPHOSPHATES AND RELATED COMPOUNDS | — | 1998-02-19 | — | — | WO | disclosed |
| WO-1998003182-A2 | USE OF URIDINE TRIPHOSPHATES AND RELATED COMPOUNDS FOR THE PREVENTION AND TREATMENT OF PNEUMONIA IN IMMOBILIZED PATIENTS | INSPIRE PHARMACEUTICALS, INC. (US) | 1998-01-29 | — | — | WO | disclosed |
| WO-1997035591-A2 | METHOD OF TREATING CILIARY DYSKINESIA WITH URIDINE TRIPHOSPHATES AND RELATED COMPOUNDS | INSPIRE PHARMACEUTICALS, INC. (US) | 1997-10-02 | — | — | WO | disclosed |
| EP-0232967-B1 | COMPETITIVE HOMOGENEOUS ASSAY | AMOCO CORPORATION (US) | 1993-04-28 | — | — | EP | disclosed |
| EP-0232967-A2 | Competitive homogeneous Assay | AMOCO CORPORATION (US) | 1987-08-19 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020155150-A1 | USE OF URIDINE TRIPHOSPHATES AND RELATED COMPOUNDS FOR THE PREVENTION AND TREATMENT OF PNEUMONIA IN IMMOBILIZED PATIENTS | UMPS, UPP1, P2RY1 | P2RX3 18/4885P2RX2 52/4885RNASEL 529/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.