Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SENP5 | Q96HI0 | 3/20 | 0.44 |
| ▸ | SENP2 | Q9HC62 | 3/20 | 0.44 |
| ▸ | SENP1 | Q9P0U3 | 3/20 | 0.44 |
| ▸ | USP2 | O75604 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | RAB9A | P51151 | 3/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | SIRT2 | Q8IXJ6 | 2/20 | 0.43 |
| ▸ | SIRT3 | Q9NTG7 | 2/20 | 0.43 |
| ▸ | CLCN2 | P51788 | 1/20 | 0.42 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.41 |
| ▸ | PLAU | P00749 | 2/20 | 0.40 |
| ▸ | MRGPRX4 | Q96LA9 | 2/20 | 0.39 |
| ▸ | MAOB | P27338 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5722819 | 0.92 | SENP5 (0.46) | SENP5SENP2SENP1MEN1KMT2A | |
| SCHEMBL5718006 | 0.91 | PLAU (0.40) | SENP5SENP2SENP1MEN1KMT2A | |
| SCHEMBL5717977 | 0.90 | MRGPRX4 (0.42) | SENP5SENP2SENP1MEN1KMT2A | |
| SCHEMBL5722619 | 0.90 | SENP5 (0.46) | SENP5SENP2SENP1MEN1KMT2A | |
| SCHEMBL5722544 | 0.89 | LMNA (0.37) | SENP5SENP2SENP1USP2MEN1 | |
| SCHEMBL5722563 | 0.88 | SENP5 (0.46) | SENP5SENP2SENP1USP2MEN1 | |
| SCHEMBL5722487 | 0.88 | ALDH1A1 (0.35) | SENP5SENP2SENP1USP2MEN1 | |
| SCHEMBL5718130 | 0.87 | MRGPRX4 (0.41) | MEN1KMT2ARAB9ANPC1MRGPRX4 | |
| SCHEMBL5119979 | 0.86 | MEN1 (0.50) | SENP5SENP2SENP1USP2MEN1 | |
| SCHEMBL5722554 | 0.85 | RHOC (0.39) | MRGPRX4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1732532-A1 | NOVEL PHARMACEUTICAL COMPOSITIONS COMPRISING AGONISTS OF THE THYROID RECEPTOR | KARO BIO AB (SE) | 2006-12-20 | — | — | EP | disclosed |
| WO-2005092316-A1 | NOVEL PHARMACEUTICAL COMPOSITIONS COMPRISING AGONISTS OF THE THYROID RECEPTOR | KARO BIO AB (SE) | 2005-10-06 | — | — | WO | disclosed |