Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLAU | P00749 | 2/20 | 0.40 |
| ▸ | MRGPRX4 | Q96LA9 | 7/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | NPC1 | O15118 | 3/20 | 0.39 |
| ▸ | RAB9A | P51151 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | SENP5 | Q96HI0 | 1/20 | 0.36 |
| ▸ | SENP2 | Q9HC62 | 1/20 | 0.36 |
| ▸ | SENP1 | Q9P0U3 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | GLA | P06280 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5722571 | 0.91 | SENP5 (0.44) | PLAUMRGPRX4KMT2ANPC1RAB9A | |
| SCHEMBL5717977 | 0.90 | MRGPRX4 (0.42) | PLAUMRGPRX4KMT2ANPC1RAB9A | |
| SCHEMBL5722619 | 0.90 | SENP5 (0.46) | PLAUMRGPRX4KMT2ANPC1RAB9A | |
| SCHEMBL5717924 | 0.89 | LMNA (0.37) | PLAUMRGPRX4KMT2ANPC1RAB9A | |
| SCHEMBL5722819 | 0.88 | SENP5 (0.46) | PLAUMRGPRX4KMT2ANPC1RAB9A | |
| SCHEMBL5717999 | 0.88 | NPC1 (0.41) | PLAUMRGPRX4KMT2ANPC1RAB9A | |
| SCHEMBL5717818 | 0.88 | HSD17B10 (0.35) | PLAUMRGPRX4KMT2ANPC1RAB9A | |
| SCHEMBL5718130 | 0.87 | MRGPRX4 (0.41) | MRGPRX4KMT2ANPC1RAB9AMEN1 | |
| SCHEMBL5717907 | 0.87 | MAPT (0.35) | PLAUMRGPRX4KMT2AMEN1MAPT | |
| SCHEMBL4924596 | 0.86 | RAB9A (0.45) | PLAUMRGPRX4KMT2ANPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1732533-A1 | THYROID RECEPTOR AGONISTS | KARO BIO AB (SE) | 2006-12-20 | — | — | EP | disclosed |
| WO-2005092317-A1 | THYROID RECEPTOR AGONISTS | KARO BIO AB (SE) | 2005-10-06 | — | — | WO | disclosed |