Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4A | P27815 | 1/20 | 0.38 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.38 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.38 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.38 |
| ▸ | ENO1 | P06733 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.37 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.37 |
| ▸ | APEX1 | P27695 | 1/20 | 0.37 |
| ▸ | THPO | P40225 | 1/20 | 0.37 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10366399 | 0.78 | CYP2C9 (0.57) | PDE4APDE4BPDE4CPDE4DENO1 | |
| SCHEMBL29362852 | 0.78 | POLB (0.38) | PDE4APDE4BPDE4CPDE4DENO1 | |
| SCHEMBL9914133 | 0.69 | ALDH1A1 (0.58) | LMNAPTGS1THPOPMP22POLB | |
| SCHEMBL9046926 | 0.65 | TSHR (0.39) | ENO1LMNAKMT2AMEN1CYP3A4 | |
| SCHEMBL9720753 | 0.64 | ALDH1A1 (0.37) | LMNATDP1GAAALDH1A1 | |
| SCHEMBL9720917 | 0.64 | ALDH1A1 (0.37) | LMNATDP1GAAALDH1A1 | |
| SCHEMBL9720921 | 0.64 | ALDH1A1 (0.37) | LMNATDP1GAAALDH1A1 | |
| SCHEMBL10263505 | 0.63 | LMNA (0.47) | ENO1LMNAKMT2AMEN1SMN1; SMN2 | |
| SCHEMBL28106918 | 0.63 | ENO1 (0.36) | ENO1LMNAKMT2AMEN1TDP1 | |
| SCHEMBL10368434 | 0.63 | MEN1 (0.50) | LMNAKMT2AMEN1CYP3A4CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-3169869-A | — | — | None | — | — | JP | disclosed |
| JP-H03169869-A | DIOXOPIPERAZINE DERIVATIVE | SANKYO CO LTD | 1991-07-23 | — | — | JP | disclosed |