Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | CRHBP | P24387 | 1/20 | 0.46 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | CTSL | P07711 | 5/20 | 0.45 |
| ▸ | CTSS | P25774 | 2/20 | 0.45 |
| ▸ | CTSK | P43235 | 2/20 | 0.45 |
| ▸ | CTSB | P07858 | 1/20 | 0.45 |
| ▸ | MMP2 | P08253 | 1/20 | 0.44 |
| ▸ | MMP3 | P08254 | 1/20 | 0.44 |
| ▸ | MMP7 | P09237 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12877478 | 0.87 | FOLH1 (0.50) | ALDH1A1HPGDLMNACTSLCYP2C19 | |
| SCHEMBL712558 | 0.87 | FOLH1 (0.50) | ALDH1A1HPGDLMNACTSLCYP2C19 | |
| SCHEMBL714529 | 0.85 | TAS1R3 (0.54) | ALDH1A1KMT2ALMNACTSLRAB9A | |
| SCHEMBL8232716 | 0.85 | TAS1R3 (0.54) | ALDH1A1KMT2ALMNACTSLRAB9A | |
| SCHEMBL2782642 | 0.85 | TAS1R3 (0.54) | ALDH1A1KMT2ALMNACTSLRAB9A | |
| SCHEMBL5759561 | 0.82 | PKM (0.57) | ALDH1A1KMT2AMEN1LMNACTSL | |
| SCHEMBL18803701 | 0.82 | CA2 (0.51) | ALDH1A1KMT2AMEN1CRHBPCRHR2 | |
| SCHEMBL12019153 | 0.81 | ALDH1A1 (0.51) | ALDH1A1KMT2AMEN1CRHBPCRHR2 | |
| SCHEMBL12984469 | 0.81 | ALDH1A1 (0.58) | ALDH1A1KMT2AMEN1HPGDLMNA | |
| SCHEMBL7371458 | 0.79 | PDE4A (0.50) | ALDH1A1KMT2AMEN1CRHBPCRHR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1423363-B1 | ORAL ANTIDIABETIC AGENTS | WARNER LAMBERT CO (US) | 2006-04-19 | — | — | EP | disclosed |
| EP-1577305-A1 | Oral antidiabetic agents | WARNER-LAMBERT COMPANY LLC (US) | 2005-09-21 | — | — | EP | disclosed |
| EP-1423363-A1 | ORAL ANTIDIABETIC AGENTS | Warner-Lambert Company LLC (US) | 2004-06-02 | — | — | EP | disclosed |
| US-20030171377-A1 | Antidiabetic agents | BIGGE CHRISTOPHER FRANKLIN (US) | 2003-09-11 | — | — | US | disclosed |
| WO-2003018553-A1 | ORAL ANTIDIABETIC AGENTS | WARNER-LAMBERT COMPANY LLC (US) | 2003-03-06 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030171377-A1 | Antidiabetic agents | SLC5A1, SLC5A2, GLP1R | ALDH1A1 874/4885KMT2A 4007/4885MEN1 1196/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.