Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FOLH1 | Q04609 | 1/20 | 0.50 |
| ▸ | ACE | P12821 | 2/20 | 0.49 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.49 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | CTSL | P07711 | 1/20 | 0.47 |
| ▸ | CTRB1 | P17538 | 1/20 | 0.46 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.46 |
| ▸ | IDO1 | P14902 | 1/20 | 0.46 |
| ▸ | CA2 | P00918 | 4/20 | 0.46 |
| ▸ | CA1 | P00915 | 2/20 | 0.46 |
| ▸ | PPARG | P37231 | 1/20 | 0.44 |
| ▸ | PPARA | Q07869 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL712558 | 1.00 | FOLH1 (0.50) | FOLH1ACEPIN1CYP2C19PTPN1 | |
| SCHEMBL5727358 | 0.87 | ALDH1A1 (0.46) | CYP2C19ALDH1A1LMNAHPGDCTSL | |
| SCHEMBL714529 | 0.84 | TAS1R3 (0.54) | ALDH1A1LMNACTSL | |
| SCHEMBL8232716 | 0.84 | TAS1R3 (0.54) | ALDH1A1LMNACTSL | |
| SCHEMBL2782642 | 0.84 | TAS1R3 (0.54) | ALDH1A1LMNACTSL | |
| SCHEMBL3187487 | 0.84 | POLB (0.49) | FOLH1PIN1CYP2C19ALDH1A1LMNA | |
| SCHEMBL5761847 | 0.82 | PKM (0.57) | FOLH1PTPN1ALDH1A1LMNACTSL | |
| SCHEMBL714183 | 0.81 | CA2 (0.57) | FOLH1ALDH1A1LMNACA2CA1 | |
| SCHEMBL11063949 | 0.81 | ACE (0.52) | ACEPTPN1ALDH1A1CTSLSLC1A2 | |
| SCHEMBL713931 | 0.81 | ICMT (0.47) | ACEPIN1CYP2C19PTPN1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1984384-B1 | Conotoxin analogues, and methods for synthesis of intramolecular dicarba bridge containing peptides | SYNGENE LTD (AU) | 2015-10-21 | — | — | EP | disclosed |
| WO-2011015241-A1 | CONFORMATIONALLY CONSTRAINED, FULLY SYNTHETIC MACROCYCLIC COMPOUNDS | POLYPHOR AG (CH) | 2011-02-10 | — | — | WO | disclosed |