Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.51 |
| ▸ | HPGD | P15428 | 3/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.51 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.51 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.51 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.51 |
| ▸ | BLM | P54132 | 1/20 | 0.51 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.51 |
| ▸ | APEX1 | P27695 | 1/20 | 0.50 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | USP2 | O75604 | 1/20 | 0.47 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5727475 | 0.85 | ALDH1A1 (0.52) | ALDH1A1HPGDCYP1A2CYP3A4CYP2D6 | |
| SCHEMBL14698338 | 0.83 | APEX1 (0.59) | ALDH1A1HPGDCYP1A2CYP3A4CYP2D6 | |
| SCHEMBL30520585 | 0.82 | APEX1 (0.58) | ALDH1A1HPGDCYP1A2CYP3A4CYP2D6 | |
| SCHEMBL21623922 | 0.82 | APEX1 (0.58) | ALDH1A1HPGDCYP1A2CYP3A4CYP2D6 | |
| SCHEMBL1031773 | 0.81 | TRPV1 (0.59) | ALDH1A1HPGDCYP1A2CYP3A4CYP2D6 | |
| SCHEMBL16245931 | 0.75 | NOX4 (0.55) | ALDH1A1HPGDCYP1A2CYP3A4CYP2D6 | |
| Nonanoate SCHEMBL29822484 | 0.75 | CYP1A2 (0.66) | ALDH1A1HPGDCYP1A2CYP3A4CYP2D6 | |
| SCHEMBL30386504 | 0.75 | APEX1 (0.56) | HPGDAPEX1TRPV1 | |
| SCHEMBL21623925 | 0.74 | HPGD (0.53) | ALDH1A1HPGDALOX15APEX1LMNA | |
| SCHEMBL26605313 | 0.74 | TRPV1 (0.56) | ALDH1A1HPGDCYP3A4ALOX15APEX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1633715-A1 | 2-(6-AMINO-PYRIDIN-3-YL)-2-HYDROXYETHYLAMINE DERIVATIVES AS BETA 2-ADRENOCEPTORS AGONISTS | Pfizer Limited (GB) | 2006-03-15 | — | — | EP | claimed |
| WO-2004108676-A1 | 2-(6-AMINO-PYRIDIN-3-YL)-2-HYDROXYETHYLAMINE DERIVATIVES AS BETA 2-ADRENOCEPTORS AGONISTS | PFIZER LIMITED (GB) | 2004-12-16 | — | — | WO | claimed |