SCHEMBL4635992

SCHEMBL4635992

Cc1cccc(Cl)c1S(=O)(=O)O

nearest known ligand 0.48

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
SLC40A1 Q9NP59 1/20 0.43
ATM Q13315 1/20 0.40
AKR1C3 P42330 1/20 0.40
CCR1 P32246 3/20 0.39
NR3C1 P04150 1/20 0.37
ESR1 P03372 1/20 0.37
TDP1 Q9NUW8 2/20 0.37
ALDH1A1 P00352 2/20 0.37
MEN1 O00255 1/20 0.37
KMT2A Q03164 1/20 0.37
KDM4E B2RXH2 1/20 0.36
POLB P06746 1/20 0.36
APEX1 P27695 1/20 0.36
GAA P10253 1/20 0.36
CNR1 P21554 1/20 0.36
HDAC4 P56524 1/20 0.36
SLC1A3 P43003 1/20 0.36
SLC1A2 P43004 1/20 0.36
TYK2 P29597 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL4303872 0.98 SLC40A1 (0.42) SLC40A1ATMAKR1C3CCR1NR3C1
SCHEMBL440935 0.84 ALDH1A1 (0.44) ATMTDP1ALDH1A1MEN1KMT2A
SCHEMBL183903 0.84 ALDH1A1 (0.43) ATMTDP1ALDH1A1KDM4EPOLB
SCHEMBL27764997 0.82 ALDH1A1 (0.42) ATMTDP1ALDH1A1KDM4EPOLB
Benzene SCHEMBL28947691 0.82 TDP1 (0.44) ATMTDP1ALDH1A1KDM4EPOLB
Iodide SCHEMBL27949560 0.82 ALDH1A1 (0.42) ATMTDP1ALDH1A1MEN1KMT2A
SCHEMBL11076120 0.82 ALDH1A1 (0.42) ATMTDP1ALDH1A1KDM4EPOLB
Water SCHEMBL8773033 0.82 ALDH1A1 (0.42) ATMTDP1ALDH1A1KDM4EPOLB
Hydrochloric Acid SCHEMBL8629651 0.82 ALDH1A1 (0.42) ATMTDP1ALDH1A1KDM4EPOLB
SCHEMBL27841017 0.82 ALDH1A1 (0.42) ATMTDP1ALDH1A1KDM4EPOLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 272 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250084085-A1 PROCESS OF MAKING 2-[(3R)-2-[4-AMINO-3-(2-FLUORO-4-PHENOXY-PHENYL)PYRAZOLO[3,4-D]PYRIMIDIN-1-YL]PIPERIDINE-1-CARBONYL]-4-METHYL-4[4-(OXETAN-3-YL)PIPERAZIN-1-YL]-PENT-2-ENENITRILE AND SOLVATE FORMS THEREOF PRINCIPIA BIOPHARMA INC. (US) 2025-03-13 US claimed
WO-2025029842-A2 PROCESS OF MAKING 2-[(3R)-2-[4-AMINO-3-(2-FLUORO-4-PHENOXY- PHENYL)PYRAZOLO[3,4-D]PYRIMIDIN-L-YL]PIPERIDINE-L-CARBONYL]-4- METHYL-4[4-(OXETAN-3-YL)PIPERAZIN-L-YL]-PENT-2-ENENITRILE AND SOLVATE FORMS THEREOF PRINCIPIA BIOPHARMA INC. (US) 2025-02-06 WO claimed
CN-111183214-B Leuco colorants as bluing agents in laundry care compositions 宝洁公司 2022-06-14 CN claimed
US-11299634-B2 Reactive leuco compounds and compositions comprising the same MILLIKEN & COMPANY (US) 2022-04-12 US claimed
US-20220089974-A1 LAUNDRY CARE COMPOSITIONS AND METHODS FOR DETERMINING THEIR AGE PROCTER & GAMBLE (US) 2022-03-24 US claimed
CN-111183215-B Laundry care compositions and methods for determining their age 宝洁公司 2022-03-15 CN claimed
US-11230686-B2 Laundry care compositions and methods for determining their age THE PROCTER & GAMBLE COMPANY (US) 2022-01-25 US claimed
CN-111194348-B Leuco colorants in combination with secondary brighteners as bluing agents in laundry care compositions 宝洁公司 2021-12-03 CN claimed
US-11142727-B2 Methods of using leuco colorants as bluing agents in laundry care compositions THE PROCTER & GAMBLE COMPANY (US) 2021-10-12 US claimed
US-11046920-B2 Methods of using leuco colorants as bluing agents in laundry care compositions THE PROCTER & GAMBLE COMPANY (US) 2021-06-29 US claimed
US-20190112559-A1 METHODS OF USING LEUCO COLORANTS AS BLUING AGENTS IN LAUNDRY CARE COMPOSITIONS THE PROCTER & GAMBLE COMPANY 2019-04-18 US claimed
US-20180148672-A1 LEUCO COLORANTS AS BLUING AGENTS IN LAUNDRY CARE COMPOSITIONS MILLIKEN & COMPANY 2018-05-31 US claimed
US-20180119068-A1 METHODS OF USING LEUCO COLORANTS AS BLUING AGENTS IN LAUNDRY CARE COMPOSITIONS THE PROCTER & GAMBLE COMPANY 2018-05-03 US claimed
US-20180118942-A1 REACTIVE LEUCO COMPOUNDS AND COMPOSITIONS COMPRISING THE SAME MILLIKEN & COMPANY 2018-05-03 US claimed
US-20180119067-A1 LEUCO COLORANTS AS BLUING AGENTS IN LAUNDRY CARE COMPOSITIONS THE PROCTER & GAMBLE COMPANY 2018-05-03 US claimed
US-20180119057-A1 METHODS OF USING LEUCO COLORANTS AS BLUING AGENTS IN LAUNDRY CARE COMPOSITIONS THE PROCTER & GAMBLE COMPANY 2018-05-03 US claimed
EP-1934187-A1 NOVEL BENZIMIDAZOLE AND BENZOTHIAZOLE DERIVATIVES, METHOD FOR PREPARING SAME, USE THEREOF AS DRUGS, PHARMACEUTICAL COMPOSITIONS AND NOVEL USE IN PARTICULAR AS C-MET INHIBITORS Aventis Pharma S.A. (FR) 2008-06-25 EP claimed
WO-2007036630-A1 NOVEL BENZIMIDAZOLE AND BENZOTHIAZOLE DERIVATIVES, METHOD FOR PREPARING SAME, USE THEREOF AS DRUGS, PHARMACEUTICAL COMPOSITIONS AND NOVEL USE IN PARTICULAR AS C-MET INHIBITORS AVENTIS PHARMA S.A. (FR) 2007-04-05 WO claimed
US-4267319-A CATIONIC DYES AND N-HETEROCYCLIC CATIONIC POLYMERS; PRINTING PAPER; ORANGE OR RED BASF AKTIENGESELLSCHAFT (DE) 1981-05-12 US claimed
US-4131619-A Preparation of 2-chloro-4-toluenesulfonyl chloride THE DOW CHEMICAL COMPANY (US) 1978-12-26 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250084085-A1 PROCESS OF MAKING 2-[(3R)-2-[4-AMINO-3-(2-FLUORO-4-PHENOXY-PHENYL)PYRAZOLO[3,4-D]PYRIMIDIN-1-YL]PIPERIDINE-1-CARBONYL]-4-METHYL-4[4-(OXETAN-3-YL)PIPERAZIN-1-YL]-PENT-2-ENENITRILE AND SOLVATE FORMS THEREOF EPB41, HTR4, HTR3C SLC40A1 2825/4885ATM 4265/4885AKR1C3 1082/4885
US-11046920-B2 Methods of using leuco colorants as bluing agents in laundry care compositions LPO, LEO1, LBR SLC40A1 199/4885ATM 1390/4885AKR1C3 3090/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.