Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | ATM | Q13315 | 2/20 | 0.42 |
| ▸ | CNR1 | P21554 | 1/20 | 0.41 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.41 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 4/20 | 0.40 |
| ▸ | AKR1B1 | P15121 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL27552065 | 0.97 | ALDH1A1 (0.42) | ALDH1A1KMT2AMEN1TDP1ATM | |
| SCHEMBL149755 | 0.88 | TTR (0.44) | ALDH1A1KMT2AMEN1TDP1ATM | |
| SCHEMBL2844949 | 0.88 | NSD2 (0.39) | ALDH1A1KMT2AMEN1TDP1ATM | |
| SCHEMBL5728040 | 0.86 | TSHR (0.48) | ALDH1A1KMT2AMEN1TDP1ATM | |
| SCHEMBL4635992 | 0.84 | SLC40A1 (0.43) | ALDH1A1KMT2AMEN1TDP1ATM | |
| SCHEMBL10296112 | 0.84 | PKM (0.47) | ALDH1A1KMT2AMEN1TDP1ATM | |
| SCHEMBL6939244 | 0.84 | TTR (0.46) | ALDH1A1KMT2AMEN1TDP1ATM | |
| SCHEMBL10955365 | 0.83 | TDP1 (0.50) | ALDH1A1KMT2AMEN1TDP1ATM | |
| Hydrochloric Acid SCHEMBL4303872 | 0.83 | SLC40A1 (0.42) | ALDH1A1KMT2AMEN1TDP1ATM | |
| SCHEMBL8206228 | 0.81 | KMT2A (0.36) | ALDH1A1KMT2AMEN1TDP1ATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 69 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8110571-B2 | Tyrosine kinase inhibitors; antiproliferation agents; metabolism diseases; antiallergens; central nervous system disorders; vision and skin disorders; antiarthritic agents | AVENTIS PHARMA S.A. (FR) | 2012-02-07 | — | — | US | claimed |
| EP-1934187-A1 | NOVEL BENZIMIDAZOLE AND BENZOTHIAZOLE DERIVATIVES, METHOD FOR PREPARING SAME, USE THEREOF AS DRUGS, PHARMACEUTICAL COMPOSITIONS AND NOVEL USE IN PARTICULAR AS C-MET INHIBITORS | Aventis Pharma S.A. (FR) | 2008-06-25 | — | — | EP | claimed |
| WO-2007036630-A1 | NOVEL BENZIMIDAZOLE AND BENZOTHIAZOLE DERIVATIVES, METHOD FOR PREPARING SAME, USE THEREOF AS DRUGS, PHARMACEUTICAL COMPOSITIONS AND NOVEL USE IN PARTICULAR AS C-MET INHIBITORS | AVENTIS PHARMA S.A. (FR) | 2007-04-05 | — | — | WO | claimed |
| US-20060094880-A9 | Synthetic process for trans-aminocyclohexyl ether compounds | BARRETT ANTHONY G M | 2006-05-04 | — | — | US | claimed |
| WO-2005016242-A2 | SYNTHETIC PROCESS FOR TRANS-AMINOCYCLOHEXYL ETHER COMPOUNDS | CARDIOME PHARMA CORP. (CA) | 2005-02-24 | — | — | WO | claimed |
| US-20050038256-A1 | Synthetic process for trans-aminocyclohexyl ether compounds | CARDIOME PHARMA CORP. (CA) | 2005-02-17 | — | — | US | claimed |
| US-20250020997-A1 | PHOTORESIST COMPOSITIONS AND METHODS OF MANUFACTURING INTEGRATED CIRCUIT DEVICES USING THE SAME | SAMSUNG ELECTRONICS CO., LTD. (KR) | 2025-01-16 | — | — | US | disclosed |
| CN-117642422-A | Structure for reducing antibody-lipase binding | 基因泰克公司 | 2024-03-01 | — | — | CN | disclosed |
| US-20230176481-A1 | FILM-FORMING COMPOSITION | NISSAN CHEMICAL CORPORATION (JP) | 2023-06-08 | — | — | US | disclosed |
| US-9586899-B2 | Synthetic process for aminocyclohexyl ether compounds | CARDIOME PHARMA CORP. (CA) | 2017-03-07 | — | — | US | disclosed |
| US-20150336887-A1 | SYNTHETIC PROCESS FOR AMINOCYCLOHEXYL ETHER COMPOUNDS | CORREVIO CANADA CORP. (CA) | 2015-11-26 | — | — | US | disclosed |
| US-9115081-B2 | Synthetic process for aminocyclohexyl ether compounds | CARDIOME PHARMA CORP. (CA) | 2015-08-25 | — | — | US | disclosed |
| EP-1676835-B1 | PROCESS FOR PRODUCING TRIARYLSULFONIUM SALT | WAKO PURE CHEM IND LTD (JP) | 2014-12-10 | — | — | EP | disclosed |
| EP-0385874-A1 | Functionalisation at position (n+1) of aryl derivatives disubstituted at position n and (n+2) | RHONE-POULENC CHIMIE (FR) | 1990-09-05 | — | — | EP | disclosed |
| EP-0224292-B1 | PROCESS FOR THE PREPARATION OF ORGANIC ISOCYANATES | SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) | 1990-04-11 | — | — | EP | disclosed |
| US-4851094-A | OXIDIZING A THIOUREA WITH HYDROGEN PEROXIDE USING A MOLYBDENUM -CONTAINING CATALYST | MCNEILAB, INC. (US) | 1989-07-25 | — | — | US | disclosed |
| US-4781866-A | Process for producing amidine sulfonic acid intermediates for guanidines | MCNEILAB, INC. (US) | 1988-11-01 | — | — | US | disclosed |
| EP-0248586-A2 | Process for producing amidine sulfonic acid intermediates for guanidines | McNeilab, Inc. (US) | 1987-12-09 | — | — | EP | disclosed |
| EP-0224292-A1 | Process for the preparation of organic isocyanates | SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) | 1987-06-03 | — | — | EP | disclosed |
| US-4656291-A | OXIDIZING THIOUREA DERIVATIVE WITH HYDROGEN PEROXIDE IN PRESENCE OF MOLYBDENUM CATALYST | MCNEILAB, INC. (US) | 1987-04-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060094880-A9 | Synthetic process for trans-aminocyclohexyl ether compounds | AKR1C3, CBR1, CBR3 | ALDH1A1 1484/4885KMT2A 3897/4885MEN1 1794/4885 |
| US-20050038256-A1 | Synthetic process for trans-aminocyclohexyl ether compounds | AKR1C3, CBR1, CBR3 | ALDH1A1 1484/4885KMT2A 3897/4885MEN1 1794/4885 |
| US-20150336887-A1 | SYNTHETIC PROCESS FOR AMINOCYCLOHEXYL ETHER COMPOUNDS | DDC, PAICS, CYP4F2 | ALDH1A1 3196/4885KMT2A 2038/4885MEN1 1043/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.